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TMEM135 Knockout Cell Lines

Gene: TMEM135

Official Full Name: transmembrane protein 135provided by HGNC

Gene Summary: Predicted to be involved in peroxisome organization. Predicted to act upstream of or within several processes, including regulation of oxidative phosphorylation; response to food; and retinal pigment epithelium development. Predicted to be located in peroxisome. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13255 TMEM135 Knockout cell line (HeLa) Human TMEM135 1:3~1:6 Negative Online Inquiry
KO13256 TMEM135 Knockout cell line (HCT 116) Human TMEM135 1:2~1:4 Negative Online Inquiry
KO13257 TMEM135 Knockout cell line (HEK293) Human TMEM135 1:3~1:6 Negative Online Inquiry
KO13258 TMEM135 Knockout cell line (A549) Human TMEM135 1:3~1:4 Negative Online Inquiry

Background

TMEM135 Gene Knockout Cell Lines are specialized cell models in which the TMEM135 gene, implicated in various cellular processes including membrane trafficking and cellular signaling, has been selectively disrupted. Through CRISPR-Cas9 gene editing technology, these knockout cell lines provide a robust platform for researchers to study the functional role of TMEM135 in both physiological and pathological conditions.

One of the key functions of the TMEM135 gene is its involvement in cellular responses to stress and its influence on the maintenance of cellular homeostasis. By creating cell lines with this gene knocked out, researchers can assess the downstream effects of its absence on various cellular pathways, including those governing cell growth, survival, and differentiation. These insights are crucial for understanding disorders related to cellular dysfunction, such as cancer and neurodegenerative diseases.

In a research context, the TMEM135 Gene Knockout Cell Lines hold significant implications, particularly in drug discovery and biological research. Their relevance extends to developing targeted therapeutic strategies and elucidating disease mechanisms. This product can facilitate in vitro studies that model disease states more accurately, allowing for enhanced translational research.

Compared to traditional cell lines, the uniqueness of TMEM135 knockout models lies in their ability to provide clear insights into gene function without the confounding effects of residual gene expression. This precision allows researchers to achieve consistent and reproducible experimental outcomes, reinforcing data validity.

For researchers and clinicians, these cell lines present an invaluable tool for dissecting complex biological phenomena associated with TMEM135, propelling advancements in therapeutic interventions. The ability to study gene function in a controlled environment accelerates the pathway from the lab to clinical applications.

Our company is dedicated to providing high-quality biological products backed by extensive research and innovation. With expertise in gene editing and cellular biology, we strive to support the scientific community's pursuit of knowledge and therapeutic advancements.

Please note that all services are for research use only. Not intended for any clinical use.

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