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TMCC2 Knockout Cell Lines

Gene: TMCC2

Official Full Name: transmembrane and coiled-coil domain family 2provided by HGNC

Gene Summary: Involved in amyloid precursor protein metabolic process. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32535 TMCC2 Knockout cell line (HeLa) Human TMCC2 1:3~1:6 Negative Online Inquiry
KO32536 TMCC2 Knockout cell line (HCT 116) Human TMCC2 1:2~1:4 Negative Online Inquiry
KO32537 TMCC2 Knockout cell line (HEK293) Human TMCC2 1:3~1:6 Negative Online Inquiry
KO32538 TMCC2 Knockout cell line (A549) Human TMCC2 1:3~1:4 Negative Online Inquiry

Background

TMCC2 Gene Knockout Cell Lines are specialized research tools developed to facilitate the investigation of TMCC2 gene function and its associated biological pathways. These cell lines are genetically engineered to express a complete knockout of the TMCC2 gene, providing a platform for researchers to study the physiological and biochemical roles of this gene in various cellular contexts.

The primary mechanism of action of these knockout cell lines involves the disruption of TMCC2 protein production, achieved through targeted CRISPR/Cas9 technology or other gene-editing methodologies. The absence of the TMCC2 gene allows for the observation of resultant phenotypic changes, enabling the elucidation of its role in critical cellular processes such as cell proliferation, differentiation, and apoptosis. This is essential for understanding diseases where TMCC2 has been implicated, such as neurodegenerative disorders and certain cancers.

Scientifically, the TMCC2 Gene Knockout Cell Lines offer vital applications in both basic and applied research. In a clinical setting, they provide insights for drug development, enabling the identification of potential therapeutic targets and the evaluation of drug efficacy on specific cellular mechanisms. Furthermore, these lines serve as a model for mimicking disease states, thereby accelerating translational research that bridges laboratory findings with clinical applications.

What sets these cell lines apart from conventional cell models is their precise genetic modifications, which directly reflect the in vivo conditions. This specificity eliminates the variability commonly present in other cell lines and enhances reproducibility in experimental results. Researchers can be confident that the findings derived from these models are a direct result of the genetic perturbation rather than confounding factors.

For researchers and clinicians looking to advance their understanding of TMCC2-related pathways, these knockout cell lines provide an invaluable resource. They facilitate streamlined experimentation and efficient data generation, making them a time-saving addition to any laboratory focused on the exploration of gene function.

Our company prides itself on its commitment to providing high-quality, reliable biological products that meet the rigorous standards of the scientific community. With a dedicated team of experts and a focus on innovation, we continue to support cutting-edge research with tools designed for success.

Please note that all services are for research use only. Not intended for any clinical use.

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