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TMCC1 Knockout Cell Lines

Gene: TMCC1

Official Full Name: transmembrane and coiled-coil domain family 1provided by HGNC

Gene Summary: Enables identical protein binding activity. Involved in several processes, including endosome fission; endosome membrane tubulation; and membrane fission. Located in cytosol; endoplasmic reticulum-endosome membrane contact site; and rough endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30011 TMCC1 Knockout cell line (HeLa) Human TMCC1 1:3~1:6 Negative Online Inquiry
KO30012 TMCC1 Knockout cell line (HCT 116) Human TMCC1 1:2~1:4 Negative Online Inquiry
KO30013 TMCC1 Knockout cell line (HEK293) Human TMCC1 1:3~1:6 Negative Online Inquiry
KO30014 TMCC1 Knockout cell line (A549) Human TMCC1 1:3~1:4 Negative Online Inquiry

Background

TMCC1 Gene Knockout Cell Lines represent a cutting-edge tool in genetic and cellular research designed to facilitate the study of TMCC1 (Transmembrane and Coiled-Coil Domain 1), a gene implicated in various biological processes including cellular signaling and membrane dynamics. These cell lines are specifically engineered to have a complete disruption of the TMCC1 gene, allowing researchers to investigate its functional role devoid of native expression.

The key mechanism by which these knockout cell lines operate is through CRISPR/Cas9 technology, which introduces targeted mutations that render the TMCC1 gene non-functional. This precise gene-editing approach enables scientists to delineate the biological pathways influenced by TMCC1, offering insights into its contributions to cellular function and the potential implications in diseases where TMCC1 misregulation occurs.

The scientific importance of TMCC1 Gene Knockout Cell Lines cannot be overstated. In research settings, they provide a vital platform for dissecting the molecular mechanisms of action associated with the TMCC1 gene, facilitating advancements in gene therapy, oncology, and neurobiology. Clinically, these cell lines could lead to breakthroughs in understanding diseases linked to TMCC1 dysfunction, such as neurodegenerative disorders or cancers, thus paving the way for targeted therapeutic strategies.

One of the main advantages of TMCC1 Gene Knockout Cell Lines is their specificity and reproducibility when compared to traditional methods of gene disruption. With validated performance and robust data supporting their use, these cell lines allow researchers to obtain consistent results that enhance the reliability of experimental outcomes. Unlike alternatives that may yield off-target effects or nonspecific gene modulation, our knockout lines provide a clean slate for analysis, ensuring clarity in experimental design.

For researchers and clinicians alike, the value of TMCC1 Gene Knockout Cell Lines lies not only in their precision but also in the multifaceted insights they enable into gene function and regulation. With rigorous quality control and extensive validation, our product contributes to the body of knowledge that can drive innovations in therapeutic development and fundamental science.

At our company, we pride ourselves on our expertise in biological research tools, committed to providing high-quality genetic and cell line models tailored to meet the demands of modern scientific inquiry.

Please note that all services are for research use only. Not intended for any clinical use.

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