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TM9SF2 Knockout Cell Lines

Gene: TM9SF2

Official Full Name: transmembrane 9 superfamily member 2provided by HGNC

Gene Summary: This gene encodes a member of the transmembrane 9 superfamily. The encoded 76 kDa protein localizes to early endosomes in human cells. The encoded protein possesses a conserved and highly hydrophobic C-terminal domain which contains nine transmembrane domains. The protein may play a role in small molecule transport or act as an ion channel. A pseudogene associated with this gene is located on the X chromosome. [provided by RefSeq, Oct 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO06764 TM9SF2 Knockout cell line (HeLa) Human TM9SF2 1:3~1:6 Negative Online Inquiry
KO06765 TM9SF2 Knockout cell line (HCT 116) Human TM9SF2 1:2~1:4 Negative Online Inquiry
KO06766 TM9SF2 Knockout cell line (HEK293) Human TM9SF2 1:3~1:6 Negative Online Inquiry
KO06767 TM9SF2 Knockout cell line (A549) Human TM9SF2 1:3~1:4 Negative Online Inquiry

Background

TM9SF2 Gene Knockout Cell Lines are specialized cellular models where the TM9SF2 gene has been effectively disrupted or "knocked out." This genetic modification enables researchers to explore the functional roles of TM9SF2, a gene implicated in various biological processes, including immune response, metabolism, and potentially cancer progression. By disabling the endogenous expression of TM9SF2, these cell lines provide a powerful tool for elucidating the gene's contributions to cellular functions, disease mechanisms, and therapeutic responses.

The key mechanism of this product lies in its targeted gene editing capabilities, typically achieved through CRISPR-Cas9 technology. This approach allows for precise alterations at the DNA level, fostering a better understanding of the gene's role within various pathways. Researchers can utilize these cell lines to examine alterations in signaling cascades, protein interactions, and phenotypic changes arising from the lack of TM9SF2 expression. As a result, TM9SF2 knockout models are invaluable in the study of gene function, drug screening, and the development of novel therapeutics.

The scientific importance of TM9SF2 Gene Knockout Cell Lines extends to their practical applications in both research and clinical environments. Researchers can leverage these models to drive innovation in cancer biology, immunology, and metabolic disorders. Furthermore, these cell lines can aid in the identification of new drug targets and contribute to the understanding of resistance mechanisms in current therapies.

Compared to conventional cell lines, the uniqueness of TM9SF2 knockout systems lies in their precision and specificity, which allow for more robust experimental designs and outcomes. Additionally, the use of genetic knockout cell lines can save time and resources in identifying gene functions versus traditional methods that rely on pharmacological inhibition or overexpression approaches.

For researchers, clinicians, and pharmaceutical companies equipped with TM9SF2 Gene Knockout Cell Lines, the value is unequivocal. These advanced models facilitate high-throughput screening, biomarker discovery, and ultimately expedite the translation of research findings into clinical applications.

As a part of our commitment to excellence in biological products, our company brings years of expertise in creating high-quality cell lines tailored to meet the rigorous demands of modern research. By choosing our TM9SF2 Gene Knockout Cell Lines, users can be assured of reliable performance and unparalleled support in their scientific endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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