Gene: THAP10
Official Full Name: THAP domain containing 10provided by HGNC
Gene Summary: This gene encodes a member of a family of proteins sharing an N-terminal Thanatos-associated domain. The Thanatos-associated domain contains a zinc finger signature similar to DNA-binding domains. This gene is part of a bidirectional gene pair on the long arm of chromosome 15 that is regulated by estrogen and may play a role in breast cancer. [provided by RefSeq, Nov 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO13425 | THAP10 Knockout cell line (HeLa) | Human | THAP10 | 1:3~1:6 | Negative | Online Inquiry |
KO13426 | THAP10 Knockout cell line (HCT 116) | Human | THAP10 | 1:2~1:4 | Negative | Online Inquiry |
KO13427 | THAP10 Knockout cell line (HEK293) | Human | THAP10 | 1:3~1:6 | Negative | Online Inquiry |
KO13428 | THAP10 Knockout cell line (A549) | Human | THAP10 | 1:3~1:4 | Negative | Online Inquiry |
THAP10 Gene Knockout Cell Lines are genetically engineered cell models specifically designed to investigate the function of the THAP10 gene. This gene is known for its role in cellular processes such as growth regulation and apoptosis. By creating knockout variants where the THAP10 gene is deactivated, researchers can better understand the gene's biological functions and its implications in various disease states, including cancer and neurodegenerative disorders.
The primary mechanism of these knockout cell lines involves the application of CRISPR-Cas9 technology, which facilitates precise editing of the genome. By introducing targeted double-strand breaks, researchers can effectively disrupt the THAP10 gene, allowing for the observation of phenotypic changes that arise from its absence. These cell lines serve as a powerful platform for examining the pathways impacted by THAP10, and how its dysregulation may contribute to disease progressions.
The scientific importance of THAP10 Gene Knockout Cell Lines lies in their broad applicability for both research and clinical settings. They offer invaluable insight into gene function and can be employed in studies aimed at discovering potential therapeutic targets. This capability positions them as essential tools in molecular biology and genetic research, particularly in the fields of cancer biology and regenerative medicine.
Compared to conventional wild-type cell lines, these knockout models provide a unique advantage by mimicking pathological conditions, which results in more relevant experimental data. Moreover, their targeted nature allows for the conservation of other genes within the cellular environment, thereby reducing the risk of off-target effects and facilitating more accurate investigations.
For researchers and clinicians, understanding the role of THAP10 can lead to novel approaches in therapeutic strategies. The ability to dissect complex biological pathways enhances the potential for drug development and innovation in treatment paradigms.
Our company is committed to advancing biological research through cutting-edge genetic tools. With extensive expertise in gene editing technologies and a deep understanding of cellular biology, we provide robust products that empower scientists and clinicians alike in their quest for groundbreaking discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.