Gene: TFAP2C
Official Full Name: transcription factor AP-2 gammaprovided by HGNC
Gene Summary: The protein encoded by this gene is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes. The encoded protein can act as either a homodimer or heterodimer with other family members and is induced during retinoic acid-mediated differentiation. It plays a role in the development of the eyes, face, body wall, limbs, and neural tube. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO35040 | TFAP2C Knockout cell line (HCT 116) | Human | TFAP2C | 1:2~1:4 | Negative | Online Inquiry |
KO35041 | TFAP2C Knockout cell line (HEK293) | Human | TFAP2C | 1:3~1:6 | Negative | Online Inquiry |
KO35042 | TFAP2C Knockout cell line (A549) | Human | TFAP2C | 1:3~1:4 | Negative | Online Inquiry |
TFAP2C Gene Knockout Cell Lines are sophisticated biological tools constructed to facilitate the study of the transcription factor AP-2 gamma, which plays a critical role in various cellular processes, including differentiation, apoptosis, and tumorigenesis. By using CRISPR-Cas9 technology, our knockout cell lines enable researchers to effectively eliminate the TFAP2C gene, allowing for precise investigation into its functions and the downstream effects of its absence on cellular behavior and gene expression.
These cell lines serve as powerful platforms to explore the significant mechanisms through which TFAP2C influences cellular pathways. Their unique ability to mimic loss-of-function scenarios enables the examination of TFAP2C's roles in development, cancer biology, and other diseases, thereby providing insights into potential therapeutic targeting. In clinical research settings, these knockout cell lines can be instrumental in preclinical drug efficacy studies, enhancing the understanding of how interventions may restore normal cellular function or suppress tumor growth.
What sets our TFAP2C Gene Knockout Cell Lines apart from alternative products is their validation through rigorous characterization, ensuring researchers receive consistent and reproducible results. The specificity of the knockout allows for the investigation of TFAP2C's role without the confounding effects commonly seen with partial knockdowns or overexpression systems. Additionally, our product is backed by expert support for experimental design and troubleshooting.
Researchers, clinicians, and biotechnology companies will find immense value in these cell lines, not only for advancing fundamental knowledge in gene regulation but also for developing new strategies in precision medicine aimed at illnesses driven by aberrant transcriptional regulation. At our company, we pride ourselves on providing high-quality biological products, leveraging cutting-edge technologies and scientific expertise to serve the needs of the global research community.
Please note that all services are for research use only. Not intended for any clinical use.
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