Gene: TELO2
Official Full Name: telomere maintenance 2provided by HGNC
Gene Summary: This gene encodes a protein that functions as an S-phase checkpoint protein in the cell cycle. The protein may also play a role in DNA repair.[provided by RefSeq, Mar 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO09159 | TELO2 Knockout cell line (HeLa) | Human | TELO2 | 1:3~1:6 | Negative | Online Inquiry |
KO09160 | TELO2 Knockout cell line (HCT 116) | Human | TELO2 | 1:2~1:4 | Negative | Online Inquiry |
KO09161 | TELO2 Knockout cell line (HEK293) | Human | TELO2 | 1:3~1:6 | Negative | Online Inquiry |
TELO2 Gene Knockout Cell Lines are specifically engineered cellular models that facilitate the investigation of the TELO2 gene’s role in cellular processes. These knockout cell lines are generated using advanced gene editing techniques such as CRISPR/Cas9, rendering them invaluable tools for understanding the functional consequences of TELO2 deficiency. TELO2 is integral in maintaining genomic stability, regulating the activity of the mTOR pathway, and influencing telomere length, all of which are crucial for proper cell growth and division.
The primary mechanism by which TELO2 influences cellular function involves its role as a scaffolding protein that interacts with various signaling complexes. This interaction is pivotal for the correct functioning of mTORC1, a critical regulator of cell growth and metabolism, and is implicated in various diseases, including cancer. By using TELO2 gene knockout cell lines, researchers can elucidate the downstream effects of mTOR signaling disruptions and their contributions to pathological conditions.
The scientific significance of TELO2 gene knockout cell lines is multifaceted. In research settings, these cell lines are essential for dissecting the molecular pathways associated with cancer, aging, and other disorders tied to cellular stress responses. Clinically, understanding these pathways may lead to novel therapeutic interventions that target specific malignancies.
Compared to conventional models, TELO2 gene knockout cell lines offer unique advantages, including precise gene editing and the ability to study phenotypic changes in real-time under controlled conditions. These toolsets are aligned with the growing need for reproducible and robust models in biomedical research.
For researchers and clinicians alike, the ability to modify TELO2 opens avenues for innovative studies that can accelerate the translation of findings from the bench to clinical applications. The directed insights facilitated by these cell lines will enhance the understanding of critical cellular processes, thereby bolstering scientific discovery.
Our company specializes in high-quality biological products, leveraging state-of-the-art genomic editing technologies to provide researchers with cutting-edge tools essential for modern scientific inquiry and biomedical advancements.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.