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TEAD3 Knockout Cell Lines

Gene: TEAD3

Official Full Name: TEA domain transcription factor 3provided by HGNC

Gene Summary: This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is predominantly expressed in the placenta and is involved in the transactivation of the chorionic somatomammotropin-B gene enhancer. Translation of this protein is initiated at a non-AUG (AUA) start codon. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO09812 TEAD3 Knockout cell line (HeLa) Human TEAD3 1:3~1:6 Negative Online Inquiry
KO09813 TEAD3 Knockout cell line (HCT 116) Human TEAD3 1:2~1:4 Negative Online Inquiry
KO09814 TEAD3 Knockout cell line (HEK293) Human TEAD3 1:3~1:6 Negative Online Inquiry
KO09815 TEAD3 Knockout cell line (A549) Human TEAD3 1:3~1:4 Negative Online Inquiry

Background

TEAD3 Gene Knockout Cell Lines are advanced cellular models engineered to lack the TEAD3 gene, which plays a crucial role in the Hippo signaling pathway and cellular development. These knockout cell lines are valuable tools for investigating the functional implications of TEAD3 in various biological processes, including cell proliferation, differentiation, and tumorigenesis. By eliminating the TEAD3 gene, researchers can observe changes in cellular behavior, allowing for a comprehensive understanding of its role in health and disease.

The key function of TEAD3 Gene Knockout Cell Lines lies in their unique ability to modulate gene expression and cellular signaling cascades associated with TEAD3. In the absence of TEAD3, researchers can study the downstream effects of disrupted Hippo signaling, facilitating insights into mechanisms regulating organ size, stem cell maintenance, and cancer progression. Additionally, these cell lines serve as an effective platform for testing potential therapeutic interventions targeting the Hippo pathway, thereby enabling drug discovery efforts.

Scientifically, TEAD3 Gene Knockout Cell Lines have substantial implications in both basic research and clinical applications. They are instrumental for studying cancer biology, as aberrant TEAD3 expression has been linked to various malignancies. Furthermore, they provide a model system for exploring regenerative medicine and tissue engineering, contributing to the development of novel treatment strategies.

Compared to alternative models, such as RNA interference or transient transfection techniques, our TEAD3 Gene Knockout Cell Lines offer a stable and reproducible genetic modification, facilitating long-term studies and experiments that require precise control over genetic variables. The permanence of the knockout ensures that observed phenotypic changes are due to the loss of TEAD3, significantly enhancing the validity of research findings.

For researchers and clinicians seeking to deepen their understanding of the Hippo pathway and its implications in disease, TEAD3 Gene Knockout Cell Lines present an invaluable resource. They pave the way for groundbreaking discoveries and help advance therapeutic strategies aimed at conditions where TEAD3 modulation is critical.

As a leader in the field of biological product development, our company prides itself on delivering high-quality, reliable cellular models that empower scientists to push the boundaries of knowledge and innovation in their respective fields.

Please note that all services are for research use only. Not intended for any clinical use.

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