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TDRD7 Knockout Cell Lines

Gene: TDRD7

Official Full Name: tudor domain containing 7provided by HGNC

Gene Summary: The protein encoded by this gene belongs to the Tudor family of proteins. This protein contains conserved Tudor domains and LOTUS domains. It is a component of RNA granules, which function in RNA processing. Mutations in this gene have been associated with cataract formation in mouse and human. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO06907 TDRD7 Knockout cell line (HeLa) Human TDRD7 1:3~1:6 Negative Online Inquiry
KO06908 TDRD7 Knockout cell line (HCT 116) Human TDRD7 1:2~1:4 Negative Online Inquiry
KO06909 TDRD7 Knockout cell line (HEK293) Human TDRD7 1:3~1:6 Negative Online Inquiry
KO06910 TDRD7 Knockout cell line (A549) Human TDRD7 1:3~1:4 Negative Online Inquiry

Background

TDRD7 Gene Knockout Cell Lines are specifically engineered cellular models designed to study the functional role of the TDRD7 gene, a critical component involved in male reproductive health and spermatogenesis. By employing CRISPR/Cas9 genome editing technology, these cell lines are devoid of functional TDRD7, enabling researchers to investigate the gene's contribution to various biological processes and its implications in infertility and related diseases.

The primary function of the TDRD7 Gene Knockout Cell Lines lies in their ability to mimic the absence of TDRD7, consequently allowing scientists to observe phenotypic changes, cellular signaling pathways, and molecular interactions that occur in its absence. These mechanisms can yield vital insights into how disruptions in TDRD7 influence spermatogenic processes and may shed light on broader reproductive biology.

In research and clinical settings, these knockout cell lines serve as valuable tools for elucidating the pathological mechanisms underlying male infertility. Their applications extend to pharmaceutical screening, where potential therapeutic compounds can be evaluated for efficacy in restoring normal function or mitigating dysfunction induced by TDRD7 loss. Furthermore, as infertility represents a significant reproductive health issue globally, understanding the implications of TDRD7 may lead to novel intervention strategies.

Unlike alternative models that may not fully recapitulate the genetic or functional aspects of TDRD7-related phenotypes, our TDRD7 Gene Knockout Cell Lines ensure precise genetic modification and robust characterization. This specificity enhances reproducibility and reliability in experiments, making them essential for both academic research and clinical diagnostics.

Researchers and clinicians seeking to further their understanding of male reproductive health or explore potential therapeutic pathways will find our TDRD7 Gene Knockout Cell Lines not only scientifically sound but also indispensable tools in a rapidly evolving field. With years of expertise in cellular biology and cutting-edge genomic technologies, our company is committed to providing high-quality biological products that drive meaningful scientific discovery and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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