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TDRD3 Knockout Cell Lines

Gene: TDRD3

Official Full Name: tudor domain containing 3provided by HGNC

Gene Summary: Enables chromatin binding activity; methylated histone binding activity; and transcription coactivator activity. Predicted to be involved in DNA topological change. Located in Golgi apparatus; cytosol; and nucleus. Part of DNA topoisomerase III-beta-TDRD3 complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25762 TDRD3 Knockout cell line (HeLa) Human TDRD3 1:3~1:6 Negative Online Inquiry
KO25763 TDRD3 Knockout cell line (HCT 116) Human TDRD3 1:2~1:4 Negative Online Inquiry
KO25764 TDRD3 Knockout cell line (HEK293) Human TDRD3 1:3~1:6 Negative Online Inquiry
KO25765 TDRD3 Knockout cell line (A549) Human TDRD3 1:3~1:4 Negative Online Inquiry

Background

TDRD3 Gene Knockout Cell Lines are genetically modified cell lines characterized by the targeted disruption of the TDRD3 gene, which encodes a key protein involved in post-transcriptional regulation and RNA biology. These cell lines are created using advanced CRISPR-Cas9 technology, enabling precise editing of the genome to facilitate functional studies of the TDRD3 gene. By knocking out TDRD3, researchers can explore the role of this protein in cellular processes such as spermatogenesis, gene expression regulation, and RNA-mediated activities, ultimately advancing our understanding of fundamental biological pathways.

The primary mechanisms through which TDRD3 influences cellular functions include its role as an RNA-binding protein and its involvement in mRNA degradation and stability processes. Consequently, TDRD3 knockout cell lines provide a unique platform for examining how protein dysfunction affects gene regulation, RNA metabolism, and overall cellular health. The applications of these cell lines extend to basic research as well as potential clinical investigations, such as cancer biology, where TDRD3 has been implicated in tumorigenesis and metastasis.

Compared to traditional gene knockout models, TDRD3 Gene Knockout Cell Lines offer several advantages, including rapid generation and the ability to study the effects of TDRD3 disruption in various cell types relevant to human disease. They also enhance reproducibility across experiments, enabling scientists to yield reliable data with reduced variability.

For researchers and clinicians alike, these cell lines represent an invaluable tool for dissecting the complexities of gene function and regulation. The insights gained from utilizing TDRD3 knockout cell lines could lead to novel therapeutic strategies aimed at correcting dysfunctions related to TDRD3.

Our company specializes in cutting-edge genetic engineering technologies, providing researchers with high-quality, ready-to-use cell lines, including TDRD3 Gene Knockout Cell Lines, to facilitate innovative research and foster advancements in the biological sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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