Gene: TCF20
Official Full Name: transcription factor 20provided by HGNC
Gene Summary: This gene encodes a transcription factor that recognizes the platelet-derived growth factor-responsive element in the matrix metalloproteinase 3 promoter. The encoded protein is thought to be a transcriptional coactivator, enhancing the activity of transcription factors such as JUN and SP1. Mutations in this gene are associated with autism spectrum disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO35099 | TCF20 Knockout cell line (HeLa) | Human | TCF20 | 1:3~1:6 | Negative | Online Inquiry |
KO35100 | TCF20 Knockout cell line (HCT 116) | Human | TCF20 | 1:2~1:4 | Negative | Online Inquiry |
KO35101 | TCF20 Knockout cell line (HEK293) | Human | TCF20 | 1:3~1:6 | Negative | Online Inquiry |
KO35102 | TCF20 Knockout cell line (A549) | Human | TCF20 | 1:3~1:4 | Negative | Online Inquiry |
TCF20 Gene Knockout Cell Lines represent a critical resource for researchers studying gene function and regulatory mechanisms in cellular biology. TCF20, or T-Cell Factor 20, serves as a transcription factor that plays a significant role in various cellular processes, including differentiation and proliferation. By utilizing knockout cell lines, researchers are able to observe the effects of TCF20 depletion on gene expression and cellular behavior, thereby uncovering the gene's contributions to both normal physiology and pathological conditions.
The unique mechanism behind these cell lines involves the targeted deletion of the TCF20 gene using advanced CRISPR-Cas9 technology, ensuring a precise and effective approach to gene editing. This allows for unequivocal delineation of TCF20’s role in cellular pathways, providing insight into its involvement in diseases such as cancer, developmental disorders, and metabolic syndromes. The knockout lines are invaluable in molecular research, facilitating experiments that would otherwise be impossible with wild-type cells.
The scientific importance of TCF20 Gene Knockout Cell Lines extends to both fundamental research and clinical applications. In research settings, these cell lines allow for high-throughput screening and validation of therapeutic targets, while in the clinic, they can contribute to the development of personalized medicine strategies, enhancing our understanding of patient-specific genetic variations.
Compared to alternative methods such as RNA interference or traditional gene knockouts, TCF20 Gene Knockout Cell Lines offer enhanced specificity and stability in gene silencing, leading to more reliable and reproducible results. Furthermore, the precise excision of the target gene reduces off-target effects, ensuring that observed changes in cellular behavior can be directly attributed to the loss of TCF20 function.
For researchers and clinicians alike, the TCF20 Gene Knockout Cell Lines are an essential tool that drives innovation and discovery in genetic research. The use of these cell lines can significantly accelerate the pace of scientific inquiry, enabling the identification of new pathways and potential therapeutic interventions.
Our company's expertise in providing high-quality, precisely engineered cell lines showcases our commitment to advancing biological research. We take pride in delivering innovative tools that empower researchers and clinicians to unlock the complexities of gene function and disease mechanisms, thereby contributing to the advancement of science and medicine.
Please note that all services are for research use only. Not intended for any clinical use.
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