Gene: TCEAL1
Official Full Name: transcription elongation factor A like 1provided by HGNC
Gene Summary: This gene encodes a member of the transcription elongation factor A (SII)-like (TCEAL) gene family. Members of this family may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. The encoded protein is similar to transcription elongation factor A/transcription factor SII and contains a zinc finger-like motif as well as a sequence related to the transcription factor SII Pol II-binding region. It may exert its effects via protein-protein interactions with other transcriptional regulators rather than via direct binding of DNA. Multiple family members are located on the X chromosome. Alternative splicing results in multiple transcript variants encoding a single isoform. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO33310 | TCEAL1 Knockout cell line (HeLa) | Human | TCEAL1 | 1:3~1:6 | Negative | Online Inquiry |
KO33311 | TCEAL1 Knockout cell line (HEK293) | Human | TCEAL1 | 1:3~1:6 | Negative | Online Inquiry |
KO33312 | TCEAL1 Knockout cell line (A549) | Human | TCEAL1 | 1:3~1:4 | Negative | Online Inquiry |
TCEAL1 Gene Knockout Cell Lines are genetically engineered cell models specifically designed to study the function and impact of the TCEAL1 gene, known to play a critical role in various cellular processes, including transcriptional regulation and response to stress. By utilizing CRISPR/Cas9 technology, these knockout cell lines effectively disrupt the TCEAL1 gene, allowing researchers to observe phenotypic changes and elucidate its biological function.
The primary mechanism involves targeted gene editing, where specific sequences of DNA are altered to inactivate the TCEAL1 gene, leading to the disruption of its protein product. Researchers can then assess the resulting cellular behaviors, including proliferation rates, apoptosis, and response to environmental stressors, providing valuable insights into the gene's role in pathophysiological processes. This makes the TCEAL1 knockout cell lines an essential tool in both basic and applied biological research.
In clinical and research settings, these knockout cell lines hold significant implications for cancer research, autoimmune diseases, and other conditions where TCEAL1 has been implicated. By understanding how the absence of this gene affects cellular functions, scientists can develop targeted therapies, advancing personalized medicine approaches.
Compared to traditional methods such as RNA interference, TCEAL1 Gene Knockout Cell Lines offer permanent gene disruption, providing more consistent and reproducible results. This durability allows for long-term experimental studies and a deeper understanding of gene function without the variability associated with transient knockdown methods.
Ultimately, TCEAL1 Gene Knockout Cell Lines represent a powerful asset for researchers and clinicians alike, offering a precise and reliable model to advance scientific discovery. Backed by our company's extensive expertise in genetic engineering and cell line development, we are dedicated to providing high-quality products that support your research objectives and clinical advancements. Choose our TCEAL1 Gene Knockout Cell Lines to enhance the depth and accuracy of your studies in gene function and therapeutic exploration.
Please note that all services are for research use only. Not intended for any clinical use.
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