Gene: TBC1D17
Official Full Name: TBC1 domain family member 17provided by HGNC
Gene Summary: Predicted to enable GTPase activator activity. Involved in retrograde transport, endosome to Golgi. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO13543 | TBC1D17 Knockout cell line (HeLa) | Human | TBC1D17 | 1:3~1:6 | Negative | Online Inquiry |
KO13544 | TBC1D17 Knockout cell line (HCT 116) | Human | TBC1D17 | 1:2~1:4 | Negative | Online Inquiry |
KO13545 | TBC1D17 Knockout cell line (HEK293) | Human | TBC1D17 | 1:3~1:6 | Negative | Online Inquiry |
KO13546 | TBC1D17 Knockout cell line (A549) | Human | TBC1D17 | 1:3~1:4 | Negative | Online Inquiry |
TBC1D17 Gene Knockout Cell Lines are genetically modified cellular models specifically designed to study the function of the TBC1D17 gene, which is implicated in various fundamental biological processes, including cellular signaling, protein trafficking, and vesicle transport. These cell lines feature a precise knockout of the TBC1D17 gene, allowing researchers to observe the physiological and pathological consequences of the gene's absence and providing critical insights into its biological role.
The key function of TBC1D17 involves its regulatory action on the RAB family of small GTPases, proteins that play a pivotal role in intracellular vesicle trafficking. By inhibiting RAB GTPases, TBC1D17 influences various pathways, including those involved in autophagy and endocytosis. Utilizing these knockout cell lines enables researchers to dissect the molecular mechanisms by which TBC1D17 governs these processes, facilitating a deeper understanding of its role in cellular homeostasis.
The scientific importance of TBC1D17 Gene Knockout Cell Lines transcends basic research, finding valuable applications in clinical settings, particularly in studies related to metabolic disorders and neurodegenerative diseases where TBC1D17 dysfunction may be a contributing factor. Such models can also be instrumental in drug discovery efforts, allowing for the evaluation of therapeutic strategies targeting related pathways.
These cell lines offer distinct advantages over traditional models, including their ability to produce reproducible results with high specificity regarding the gene of interest. Unlike other genetic modification methods, the knockout approach ensures that the effects observed are directly attributable to the absence of TBC1D17, minimizing off-target effects. Designed with user-friendly protocols, these cell lines are readily adaptable for various experimental conditions, making them accessible for both seasoned researchers and newcomers to gene editing techniques.
In essence, the TBC1D17 Gene Knockout Cell Lines represent a critical tool for advancing our understanding of cellular mechanisms, making them invaluable for researchers and clinicians alike. Our company is dedicated to providing high-quality, innovative biological products tailored to meet the needs of the scientific community, and our expertise in gene editing ensures that you have access to the most reliable and effective research tools available.
Please note that all services are for research use only. Not intended for any clinical use.
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