Gene: TBC1D10B
Official Full Name: TBC1 domain family member 10Bprovided by HGNC
Gene Summary: Small G proteins of the RAB family (see MIM 179508) function in intracellular vesicle trafficking by switching from the GTP-bound state to the GDP-bound state with the assistance of guanine nucleotide exchange factors (GEFs; see MIM 609700) and GTPase-activating proteins (GAPs). TBC1D10B functions as a GAP for several proteins of the Rab family (Ishibashi et al., 2009 [PubMed 19077034]).[supplied by OMIM, Nov 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28501 | TBC1D10B Knockout cell line (HeLa) | Human | TBC1D10B | 1:3~1:6 | Negative | Online Inquiry |
KO28502 | TBC1D10B Knockout cell line (HCT 116) | Human | TBC1D10B | 1:2~1:4 | Negative | Online Inquiry |
KO28503 | TBC1D10B Knockout cell line (HEK293) | Human | TBC1D10B | 1:3~1:6 | Negative | Online Inquiry |
KO28504 | TBC1D10B Knockout cell line (A549) | Human | TBC1D10B | 1:3~1:4 | Negative | Online Inquiry |
TBC1D10B Gene Knockout Cell Lines are specialized cellular models engineered to selectively deactivate the TBC1D10B gene, which plays an essential role in various cellular processes, including vesicle trafficking and cell signaling. By utilizing CRISPR-Cas9 technology, these knockout cell lines provide researchers with a precise tool to elucidate the functional implications of TBC1D10B deficiency, thereby enabling the study of its involvement in diseases such as cancer, metabolic disorders, and neurodegenerative conditions.
The primary mechanism of action involves the introduction of targeted mutations in the TBC1D10B gene, leading to the loss of protein expression. This allows researchers to investigate the downstream effects of TBC1D10B in biological pathways, offering insights into its potential role as a therapeutic target. Furthermore, these knockout cell lines are critical in dissecting the molecular mechanisms underlying the physiological changes resulting from gene deletion, providing a clearer understanding of pathogenesis and disease progression.
From a scientific standpoint, TBC1D10B Gene Knockout Cell Lines are invaluable in both basic and applied research settings. They serve as powerful tools for drug screening, biomarker discovery, and validating therapeutic strategies targeting TBC1D10B-related pathways, ultimately facilitating advancements in personalized medicine.
What sets our TBC1D10B Gene Knockout Cell Lines apart from alternatives is their robust performance, reproducibility, and the comprehensive validation of gene knockout efficiency, ensuring consistent results across experiments. Additionally, our product complies with the highest quality standards, providing researchers confidence in the reliability of their findings.
In summary, TBC1D10B Gene Knockout Cell Lines represent a pivotal innovation for researchers and clinicians aiming to explore gene function and its implications in health and disease. Our company, with a legacy of excellence in biological product development, is committed to supplying high-quality cellular models that empower scientific discovery and innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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