Gene: TARS3
Official Full Name: threonyl-tRNA synthetase 3provided by HGNC
Gene Summary: Predicted to enable threonine-tRNA ligase activity. Predicted to be involved in threonyl-tRNA aminoacylation. Predicted to be located in cytoplasm and nucleus. Predicted to be active in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28879 | TARS3 Knockout cell line (HeLa) | Human | TARS3 | 1:3~1:6 | Negative | Online Inquiry |
KO28880 | TARS3 Knockout cell line (HCT 116) | Human | TARS3 | 1:2~1:4 | Negative | Online Inquiry |
KO28881 | TARS3 Knockout cell line (HEK293) | Human | TARS3 | 1:3~1:6 | Negative | Online Inquiry |
KO28882 | TARS3 Knockout cell line (A549) | Human | TARS3 | 1:3~1:4 | Negative | Online Inquiry |
TARS3 Gene Knockout Cell Lines are genetically modified cell lines that have undergone targeted gene editing to disrupt the TARS3 gene, which encodes for the enzyme threonyl-tRNA synthetase. This enzyme is crucial in the aminoacylation of tRNA, facilitating the proper translation of proteins and influencing cell metabolism and growth. By knocking out the TARS3 gene, researchers can investigate the role of threonyl-tRNA synthetase in various biological processes and disease mechanisms, providing insights into cellular homeostasis and the potential impact on therapeutic targets.
These cell lines exhibit a unique mechanism for studying knockdown effects, enabling scientists to explore the consequences of TARS3 in various contexts such as cancer biology, mitochondrial function, and cellular stress responses. Researchers can utilize TARS3 gene knockout cell lines to model genetic disorders caused by improper tRNA synthesis, providing a powerful tool for elucidating the underlying molecular pathways and identifying potential drug targets.
The scientific importance of TARS3 Gene Knockout Cell Lines extends to both basic and applied research. In clinical settings, these cell lines can contribute to the development of novel therapeutic strategies aimed at correcting dysregulated processes associated with insufficient or excessive TARS3 activity.
What sets TARS3 Gene Knockout Cell Lines apart from alternatives is their precise gene editing, which ensures reliable and reproducible results. Unlike traditional knockdown methods that can yield variable effects, these knockout lines provide a robust platform for functional assays and in-depth molecular studies.
For researchers and clinicians alike, the value of TARS3 Gene Knockout Cell Lines lies not only in their capability to enhance understanding of translational biology but also in their potential to accelerate the discovery of innovative solutions for complex diseases. As a company with extensive expertise in genetic engineering and cellular models, we offer these cell lines as part of our commitment to empowering research and advancing medical science.
Please note that all services are for research use only. Not intended for any clinical use.
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