Gene: TAF15
Official Full Name: TATA-box binding protein associated factor 15provided by HGNC
Gene Summary: This gene encodes a member of the TET family of RNA-binding proteins. The encoded protein plays a role in RNA polymerase II gene transcription as a component of a distinct subset of multi-subunit transcription initiation factor TFIID complexes. Translocations involving this gene play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene may play a role in amyotrophic lateral sclerosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO00060 | TAF15 Knockout cell line (Caco-2) | Human | TAF15 | 1:2~1:4 | Negative | Online Inquiry |
KO34305 | TAF15 Knockout cell line (HeLa) | Human | TAF15 | 1:3~1:6 | Negative | Online Inquiry |
KO34306 | TAF15 Knockout cell line (HCT 116) | Human | TAF15 | 1:2~1:4 | Negative | Online Inquiry |
KO34307 | TAF15 Knockout cell line (HEK293) | Human | TAF15 | 1:3~1:6 | Negative | Online Inquiry |
KO34308 | TAF15 Knockout cell line (A549) | Human | TAF15 | 1:3~1:4 | Negative | Online Inquiry |
TAF15 Gene Knockout Cell Lines are genetically modified cellular models designed to facilitate the study of the TAF15 gene, which is implicated in various biological processes and disease states, including neurodegenerative disorders and cancer. These cell lines are engineered through targeted genome editing techniques to inactivate the TAF15 gene, thereby allowing researchers to explore the functional consequences of its absence on cellular behavior, signaling pathways, and overall cellular physiology.
The key functionality of TAF15 Gene Knockout Cell Lines lies in their ability to serve as a platform for examining the role of TAF15 in transcriptional regulation and RNA metabolism. By providing an environment where the gene of interest is absent, scientists can investigate downstream effects and alternative pathways activated in response to the loss of TAF15, enhancing our understanding of its biological significance.
Scientifically, these knockout cell lines are invaluable for research studies focused on gene function analysis, drug development, and the mechanistic exploration of disease. They allow for high-throughput screening of compounds targeting pathways influenced by TAF15, paving the way for novel therapeutic strategies. In clinical settings, understanding the role of TAF15 can aid in designing targeted therapies for conditions where this gene's activity deviates from the norm.
What sets TAF15 Gene Knockout Cell Lines apart from alternative models is their precision and reliability. Unlike traditional knockdown methods, which provide only transient effects, these knockout cell lines offer stable and reproducible gene inactivation, enabling long-term studies and more accurate data collection. Additionally, they are fully validated and characterized, ensuring that researchers receive consistent results.
For researchers and clinicians focused on advancing knowledge in molecular biology and the development of innovative therapeutics, TAF15 Gene Knockout Cell Lines represent a powerful tool. Their ability to elucidate gene function in a robust and controlled environment translates to significant insights and practical applications in experimental and clinical research.
Our company specializes in providing high-quality biological products tailored to the needs of the research community, ensuring that our offerings, including the TAF15 Gene Knockout Cell Lines, meet the rigorous standards of scientific excellence demanded by today's researchers.
Please note that all services are for research use only. Not intended for any clinical use.
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