Gene: SYT11
Official Full Name: synaptotagmin 11provided by HGNC
Gene Summary: This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that are known calcium sensors and mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. The encoded protein is also a substrate for ubiquitin-E3-ligase parkin. The gene has previously been referred to as synaptotagmin XII but has been renamed synaptotagmin XI to be consistent with mouse and rat official nomenclature. [provided by RefSeq, Apr 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29684 | SYT11 Knockout cell line (HeLa) | Human | SYT11 | 1:3~1:6 | Negative | Online Inquiry |
KO29685 | SYT11 Knockout cell line (HEK293) | Human | SYT11 | 1:3~1:6 | Negative | Online Inquiry |
KO29686 | SYT11 Knockout cell line (A549) | Human | SYT11 | 1:3~1:4 | Negative | Online Inquiry |
SYT11 Gene Knockout Cell Lines are sophisticated biological research tools engineered specifically to facilitate the study of the SYT11 gene, which encodes for synaptotagmin-11, a protein linked to neurotransmitter release and synaptic function. These cell lines are generated using advanced genetic techniques, such as CRISPR/Cas9, allowing for precise and reliable knockout of the SYT11 gene, thereby enabling researchers to explore its biological roles and the consequences of its absence on cellular mechanisms.
The primary function of SYT11 Gene Knockout Cell Lines lies in their ability to model the physiological effects of SYT11 deficiency, providing insights into synaptic transmission processes and potential neurological disorders related to dysfunctions in this pathway. By observing the differences in neurotransmitter release patterns, calcium signaling, and synaptic integrity compared to wild-type strains, researchers can elucidate the specific contributions of SYT11 in both health and disease contexts.
The scientific significance of these cell lines extends to diverse applications within both research and clinical settings. They serve as valuable models for understanding neurodegenerative diseases and psychiatric disorders, thereby paving the way for the discovery of novel therapeutic targets and interventions. Their utility in drug screening and biomarker identification further underpins their relevance in translational research.
Compared to other genetic modification techniques, the SYT11 Gene Knockout Cell Lines provide a streamlined, efficient approach that ensures reproducibility and robustness in experimental outcomes. Their precise genetic modifications allow for clearer interpretations of experimental data and a deeper understanding of gene function without the confounding variables often present in other models.
For researchers and clinicians, the availability of SYT11 Gene Knockout Cell Lines translates to an invaluable resource that drives innovation in neuroscience research, offers new perspectives on synaptic health, and ultimately contributes to the advancement of treatment strategies for mental health conditions and neurological disorders.
Our company prides itself on its commitment to providing high-quality biological products that empower the scientific community. With a focus on innovation and excellence, we support researchers in their quest to unlock the mysteries of human health and disease through advanced cellular models.
Please note that all services are for research use only. Not intended for any clinical use.
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