Gene: SYNGR1
Official Full Name: synaptogyrin 1provided by HGNC
Gene Summary: This gene encodes an integral membrane protein associated with presynaptic vesicles in neuronal cells. The exact function of this protein is unclear, but studies of a similar murine protein suggest that it functions in synaptic plasticity without being required for synaptic transmission. The gene product belongs to the synaptogyrin gene family. Three alternatively spliced variants encoding three different isoforms have been identified. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO33537 | SYNGR1 Knockout cell line (HeLa) | Human | SYNGR1 | 1:3~1:6 | Negative | Online Inquiry |
KO33538 | SYNGR1 Knockout cell line (HCT 116) | Human | SYNGR1 | 1:2~1:4 | Negative | Online Inquiry |
KO33539 | SYNGR1 Knockout cell line (HEK293) | Human | SYNGR1 | 1:3~1:6 | Negative | Online Inquiry |
KO33540 | SYNGR1 Knockout cell line (A549) | Human | SYNGR1 | 1:3~1:4 | Negative | Online Inquiry |
SYNGR1 Gene Knockout Cell Lines are a unique and advanced biological research tool designed to facilitate the study of the SYNGR1 gene's functions and implications in various cellular processes and diseases. These cell lines have been meticulously engineered to have a complete and specific knockout of the SYNGR1 gene, enabling researchers to investigate the gene’s role in synaptic formation, neural connectivity, and potential neurodegenerative disorders without the influence of its protein product.
The mechanism underlying the effectiveness of these knockout cell lines lies in their precise genome editing, typically utilizing CRISPR-Cas9 technology. This ensures that the SYNGR1 gene is not only disrupted but also allows for the evaluation of downstream effects in signaling pathways, gene expression patterns, and overall cellular behavior. By observing the physiological and biochemical alterations that occur in the absence of SYNGR1, researchers can elucidate its functional contributions to health and disease.
The scientific importance of SYNGR1 Gene Knockout Cell Lines extends into numerous research domains, particularly neurobiology and pharmacology. They are invaluable in identifying novel therapeutic targets for neurodegenerative diseases, as well as testing the efficacy of new drugs in a controlled environment that mirrors physiological disorders. In clinical settings, these knockout models can accelerate the understanding of patient-specific genetic variants of SYNGR1 and their direct impact on neural health.
Compared to alternative models such as wild-type cell lines or animal models, SYNGR1 Gene Knockout Cell Lines present unique advantages in terms of specificity and reproducibility. Researchers can achieve a more consistent phenotype, enabling better data interpretation and minimizing variability that often complicates experimental outcomes. This enhanced reliability positions our product as an essential tool in the arsenal of molecular biologists and neuroscientists.
In summary, SYNGR1 Gene Knockout Cell Lines offer researchers and clinicians a powerful capability to dissect the biological roles and therapeutic potentials of the SYNGR1 gene. By providing precise models, we equip scientists with the means to push forward their research agendas effectively. Our company leverages a wealth of expertise in genetic engineering and cell line development, ensuring that our offerings support the cutting-edge work being conducted in laboratories worldwide.
Please note that all services are for research use only. Not intended for any clinical use.
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