Gene: SYDE1
Official Full Name: synapse defective Rho GTPase homolog 1provided by HGNC
Gene Summary: The protein encoded by this gene is a Rho GTPase-activating protein highly expressed in placenta. The encoded protein is involved in cytoskeletal remodeling and trophoblast cell migration. Decreased expression of this gene has been associated with intrauterine growth restriction (IUGR). [provided by RefSeq, Feb 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24266 | SYDE1 Knockout cell line (HeLa) | Human | SYDE1 | 1:3~1:6 | Negative | Online Inquiry |
KO24267 | SYDE1 Knockout cell line (HCT 116) | Human | SYDE1 | 1:2~1:4 | Negative | Online Inquiry |
KO24268 | SYDE1 Knockout cell line (HEK293) | Human | SYDE1 | 1:3~1:6 | Negative | Online Inquiry |
KO24269 | SYDE1 Knockout cell line (A549) | Human | SYDE1 | 1:3~1:4 | Negative | Online Inquiry |
SYDE1 Gene Knockout Cell Lines represent a groundbreaking innovation in gene editing technology, offering researchers a powerful tool to investigate the biological roles of the SYDE1 gene. These cell lines have been meticulously engineered using CRISPR/Cas9 technology to create precise deletions in the SYDE1 gene, enabling scientists to examine the impacts of its loss on cellular functions and molecular pathways.
The primary function of the SYDE1 Gene Knockout Cell Lines is to serve as a model for studying gene function and associated phenotypic changes. By eliminating the SYDE1 gene's expression, researchers can explore various biological processes, including cell proliferation, differentiation, and response to stressors. These knockout models facilitate comprehensive assessments of SYDE1's involvement in diseases, including neurodegenerative disorders and cancers, making them invaluable for both basic research and translational studies.
The scientific significance of these cell lines is underscored by their application in preclinical drug testing and therapeutic interventions. By understanding SYDE1's role in specific pathways, researchers can identify potential targets for novel treatment strategies, thereby expediting the development of innovative therapies. Furthermore, the availability of these well-characterized knockout models enhances reproducibility and reliability in research, a crucial factor in academic and clinical settings.
One of the standout advantages of SYDE1 Gene Knockout Cell Lines over alternative methods is the precision and efficiency with which gene disruption is achieved. Unlike older techniques, which may give rise to off-target effects or variable expression levels, our CRISPR-edited lines guarantee stability and uniformity, optimizing experimental outcomes. Additionally, they come with comprehensive documentation and validation to ensure users can trust in the consistency of their results.
For researchers and clinicians aiming to unlock the mysteries of gene function or develop targeted interventions, SYDE1 Gene Knockout Cell Lines present a compelling choice. Their robust design, coupled with the transformative potential of CRISPR technology, positions them as a critical asset for advancing our understanding of complex biological systems.
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