Gene: SYCE1
Official Full Name: synaptonemal complex central element protein 1provided by HGNC
Gene Summary: This gene encodes a member of the synaptonemal complex, which links homologous chromosomes during prophase I of meiosis. The tripartite structure of the complex is highly conserved amongst metazoans. It consists of two lateral elements and a central region formed by transverse elements and a central element. The protein encoded by this gene localizes to the central element and is required for initiation and elongation of the synapsis. Allelic variants of this gene have been associated with premature ovarian failure and spermatogenic failure. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO22184 | SYCE1 Knockout cell line (HEK293) | Human | SYCE1 | 1:3~1:6 | Negative | Online Inquiry |
SYCE1 Gene Knockout Cell Lines are a specialized type of genetically engineered cells in which the SYCE1 gene has been precisely disrupted to elucidate its biological functions and role in cellular processes. These cell lines serve as vital tools in molecular biology and genetics, enabling researchers to study the effects of the absence of SYCE1, a gene implicated in meiosis and synapsis during gamete formation.
The primary function of SYCE1 Gene Knockout Cell Lines is to provide a model system to explore the impact of SYCE1 on various biological pathways including DNA repair, chromosomal behavior during meiosis, and the regulation of gene expression. By employing CRISPR-Cas9 genome-editing technology, these cell lines ensure that the knockout is specific, efficient, and reliable, facilitating the investigation of the gene's precise role and interactions with other signaling pathways.
From a scientific standpoint, SYCE1 Gene Knockout Cell Lines have significant applications in both research and clinical settings, particularly in fields focused on reproductive biology, cancer research, and genetic disorders. Their use in the assessment of drug responses and the impact of genetic modifications provides essential data that can lead to novel therapeutic strategies.
What sets our SYCE1 Gene Knockout Cell Lines apart is their unparalleled specificity and reproducibility compared to other models that induce gene silencing through less precise methods, such as RNA interference. Furthermore, these cell lines are meticulously quality-controlled to ensure that they meet the highest standards for scientific research, thus expediting the process of hypothesis testing and data validation for our customers.
Investing in our SYCE1 Gene Knockout Cell Lines provides researchers and clinicians with a unique opportunity to explore genetic underpinnings of various biological phenomena and disease mechanisms. Our expertise in developing advanced biological products assures that you are receiving a reliable tool tailored to enhance your experimental outcomes. Through our commitment to innovation and quality, we empower scientists to push the boundaries of discovery and therapeutic development.
Please note that all services are for research use only. Not intended for any clinical use.
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