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SWAP70 Knockout Cell Lines

Gene: SWAP70

Official Full Name: switching B cell complex subunit SWAP70provided by HGNC

Gene Summary: Enables cadherin binding activity. Predicted to be involved in regulation of small GTPase mediated signal transduction. Predicted to act upstream of or within isotype switching. Located in actin cytoskeleton; cytoplasm; and plasma membrane. Is active in postsynapse. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29910 SWAP70 Knockout cell line (HeLa) Human SWAP70 1:3~1:6 Negative Online Inquiry
KO29911 SWAP70 Knockout cell line (HCT 116) Human SWAP70 1:2~1:4 Negative Online Inquiry
KO29912 SWAP70 Knockout cell line (HEK293) Human SWAP70 1:3~1:6 Negative Online Inquiry
KO29913 SWAP70 Knockout cell line (A549) Human SWAP70 1:3~1:4 Negative Online Inquiry

Background

SWAP70 Gene Knockout Cell Lines are engineered cellular models characterized by the deliberate deletion of the SWAP70 gene, which is known to play a critical role in various cellular processes, including immune responses and cell signaling. These cell lines allow researchers to elucidate the functions of SWAP70 and its influence on cellular mechanisms by providing a platform for studying gene-specific responses in a controlled environment.

The key function of these cell lines lies in their ability to mimic the phenotype associated with SWAP70 deficiencies, facilitating investigations into downstream signaling pathways, particularly those involved in lymphocyte activation and differentiation. Researchers can manipulate environmental factors and assess the cellular responses to various stimuli, yielding insights into the molecular underpinnings of autoimmune diseases and cancer, where SWAP70 activity has been implicated.

The scientific importance of SWAP70 Gene Knockout Cell Lines is vast, with applications in both basic research and clinical settings. By utilizing these models, scientists can explore gene function in a variety of experimental conditions, identifying novel therapeutic targets. In clinical research, understanding SWAP70's role in immune regulation can lead to advancements in the development of immunotherapies, making these cell lines valuable tools in translational research.

Compared to conventional models, SWAP70 Gene Knockout Cell Lines offer distinct advantages, including specificity in gene targeting and the ability to reveal the effects of SWAP70 absence without the confounding variables associated with whole-organism studies. Their reproducibility and consistency enhance experimental reliability and data integrity, setting them apart from primary cell cultures or traditional knockout animal models.

For researchers, clinicians, and pharmaceutical developers, the value of these cell lines cannot be overstated. They provide critical insights into gene function, facilitating groundbreaking discoveries in immunology and cell biology. With our commitment to advancing biological research through high-quality products, our expertise in developing tailored cell lines ensures that you have the right tools to unlock the complexities of cellular mechanisms.

Please note that all services are for research use only. Not intended for any clinical use.

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