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SUPT3H Knockout Cell Lines

Gene: SUPT3H

Official Full Name: SPT3 homolog, SAGA and STAGA complex componentprovided by HGNC

Gene Summary: Enables transcription coactivator activity. Involved in regulation of transcription by RNA polymerase II. Located in nucleoplasm. Part of SAGA complex and transcription factor TFTC complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34158 SUPT3H Knockout cell line (HeLa) Human SUPT3H 1:3~1:6 Negative Online Inquiry
KO34159 SUPT3H Knockout cell line (HCT 116) Human SUPT3H 1:2~1:4 Negative Online Inquiry
KO34160 SUPT3H Knockout cell line (HEK293) Human SUPT3H 1:3~1:6 Negative Online Inquiry
KO34161 SUPT3H Knockout cell line (A549) Human SUPT3H 1:3~1:4 Negative Online Inquiry

Background

SUPT3H Gene Knockout Cell Lines are engineered cellular models designed to investigate the functional implications of the SUPT3H gene, which is essential for RNA transcription and processing. These cell lines are meticulously generated using CRISPR-Cas9 technology, allowing for precise gene editing that results in the complete absence of SUPT3H expression. This innovative approach enables researchers to explore the consequences of gene loss on cellular processes, signaling pathways, and overall cell viability.

The key function of these knockout cell lines lies in their ability to serve as robust platforms for examining the role of SUPT3H in diverse biological contexts. By disrupting the SUPT3H gene, scientists can assess downstream effects on transcriptional regulation, mRNA stability, and protein synthesis. This is particularly valuable in understanding diseases linked to dysfunctions in transcriptional machinery, including various types of cancer and developmental disorders.

The scientific importance of SUPT3H Gene Knockout Cell Lines is underscored by their applications in both basic research and therapeutic development. They facilitate high-throughput screening, drug discovery, and validation of potential therapeutic targets, making them indispensable tools in molecular biology, pharmacology, and genetics. Researchers can effectively utilize these models to deepen their understanding of gene function and to elucidate the mechanistic pathways that underlie cellular responses to various stimuli.

Compared to alternative models, such as wild-type or other mutated cell lines, the specificity and reliability of SUPT3H Gene Knockout Cell Lines offer a clear advantage. These lines enable a more accurate interpretation of results, as they eliminate confounding variables associated with residual gene function or compensatory mechanisms. Furthermore, our commitment to offering high-quality, reproducible biological products ensures that researchers can depend on our cell lines for consistent results across experiments.

In summary, SUPT3H Gene Knockout Cell Lines stand out as vital research tools for the scientific community, providing valuable insights into gene function and its implications in disease. As a company dedicated to the advancement of biological sciences, we leverage our expertise and state-of-the-art technologies to deliver innovative products that enhance research and contribute to medical breakthroughs.

Please note that all services are for research use only. Not intended for any clinical use.

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