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SULT4A1 Knockout Cell Lines

Gene: SULT4A1

Official Full Name: sulfotransferase family 4A member 1provided by HGNC

Gene Summary: This gene encodes a member of the sulfotransferase family. The encoded protein is a brain-specific sulfotransferase believed to be involved in the metabolism of neurotransmitters. Polymorphisms in this gene may be associated with susceptibility to schizophrenia. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28748 SULT4A1 Knockout cell line (HeLa) Human SULT4A1 1:3~1:6 Negative Online Inquiry
KO28749 SULT4A1 Knockout cell line (HCT 116) Human SULT4A1 1:2~1:4 Negative Online Inquiry

Background

SULT4A1 Gene Knockout Cell Lines are custom-engineered cellular models designed to specifically disrupt the SULT4A1 gene, a key component involved in the sulfonation process of various small molecules, including neurotransmitters and drugs. This innovative product enables researchers to investigate the role of SULT4A1 in cellular metabolism and pharmacogenetics by providing a clear understanding of how its absence influences biochemical pathways and phenotypic outcomes.

These cell lines operate on a foundational mechanism of CRISPR-Cas9 technology to achieve their knockout status, ensuring precise editing of the SULT4A1 gene. When applied, this mechanism allows for targeted disruptions that lead to measurable variations in enzyme activity, cellular responses, and metabolic profiling, making them highly valuable for elucidating drug interactions and metabolic disorders related to sulfonation.

In the realm of scientific research and clinical applications, SULT4A1 Gene Knockout Cell Lines hold significant importance. They serve as powerful tools in pharmacology and toxicology studies, enabling the identification of potential biomarkers and the investigation of individual variability in drug responses. By leveraging these knockout models, researchers can enhance the development of therapeutic strategies tailored to patient-specific metabolic profiles, ultimately contributing to personalized medicine.

One key advantage of our SULT4A1 Gene Knockout Cell Lines is their unparalleled specificity and reliability. Unlike conventional models, which may exhibit compensatory mechanisms or variability, our engineered cell lines provide consistent results across experiments, thus enhancing reproducibility. Furthermore, they can be employed in high-throughput screening formats, substantially accelerating the discovery process while minimizing resource expenditure.

Investing in SULT4A1 Gene Knockout Cell Lines represents a strategic addition to any laboratory focused on cutting-edge research in drug development and metabolic studies. Their comprehensive profiling potential allows for deeper insight into metabolic pathways, supporting innovations in therapeutic solutions.

At our company, we pride ourselves on delivering high-quality biological products backed by extensive expertise in genetic engineering and cellular biology, ensuring that you receive not only innovative products but also a commitment to excellence in scientific research.

Please note that all services are for research use only. Not intended for any clinical use.

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