Gene: STX11
Official Full Name: syntaxin 11provided by HGNC
Gene Summary: This gene encodes a member of the syntaxin family. Syntaxins have been implicated in the targeting and fusion of intracellular transport vesicles. This family member may regulate protein transport among late endosomes and the trans-Golgi network. Mutations in this gene have been associated with familial hemophagocytic lymphohistiocytosis. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO33955 | STX11 Knockout cell line (HeLa) | Human | STX11 | 1:3~1:6 | Negative | Online Inquiry |
KO33956 | STX11 Knockout cell line (HEK293) | Human | STX11 | 1:3~1:6 | Negative | Online Inquiry |
STX11 Gene Knockout Cell Lines are specialized cellular models created to facilitate the study of the syntaxin 11 (STX11) gene and its associated biological pathways. These cell lines are engineered through CRISPR-Cas9 gene editing technology to achieve a complete knockout of the STX11 gene, thus providing a powerful tool for researchers investigating the functional roles of STX11 in various physiological and pathological contexts.
The primary function of the STX11 gene is to encode a protein that plays a crucial role in the membrane trafficking and secretion pathways, particularly in the immune system's response to infections. By utilizing these knockout cell lines, researchers can elucidate the contributions of STX11 to cellular processes such as cytokine release, granule exocytosis, and immune cell signaling. The detailed mechanisms facilitated by STX11 are particularly relevant for understanding the etiology of immune-related disorders and certain hematological malignancies.
Scientifically, the STX11 Gene Knockout Cell Lines hold significant importance in research settings. They aid in the discovery of the molecular underpinnings of diseases linked to dysfunctional STX11, such as familial hemophagocytic lymphohistiocytosis (HLH). In clinical applications, findings derived from such studies may inform therapeutic strategies and interventions that harness or modify immunological responses, thus paving the way for advancements in precision medicine.
What sets our STX11 Gene Knockout Cell Lines apart from alternatives is their high specificity and efficiency achieved through advanced genetic engineering techniques. Unlike conventional knockdown models that may retain partial gene function, our knockout lines ensure a complete absence of the STX11 protein, thereby providing robust, reproducible results that greatly enhance the reliability of experimental outcomes.
For researchers and clinicians alike, the value of utilizing STX11 Gene Knockout Cell Lines lies in their potential to accelerate discoveries, spark innovative therapeutic designs, and drive the understanding of immune responses at a molecular level. With our commitment to excellence and cutting-edge methodologies, our company stands ready to support the scientific community with rigorously developed biological products designed for transformative research.
Please note that all services are for research use only. Not intended for any clinical use.
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