Gene: STRN3
Official Full Name: striatin 3provided by HGNC
Gene Summary: Enables armadillo repeat domain binding activity; enzyme binding activity; and protein-macromolecule adaptor activity. Involved in negative regulation of hippo signaling; negative regulation of transcription by RNA polymerase II; and positive regulation of transcription by RNA polymerase II. Located in Golgi apparatus; nucleoplasm; and plasma membrane. Part of FAR/SIN/STRIPAK complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26889 | STRN3 Knockout cell line (HeLa) | Human | STRN3 | 1:3~1:6 | Negative | Online Inquiry |
KO26890 | STRN3 Knockout cell line (HCT 116) | Human | STRN3 | 1:2~1:4 | Negative | Online Inquiry |
KO26891 | STRN3 Knockout cell line (HEK293) | Human | STRN3 | 1:3~1:6 | Negative | Online Inquiry |
KO26892 | STRN3 Knockout cell line (A549) | Human | STRN3 | 1:3~1:4 | Negative | Online Inquiry |
STRN3 Gene Knockout Cell Lines represent a significant advancement in molecular biology and genetic research, specifically designed to facilitate in-depth studies of the striatin-3 (STRN3) gene's role in cellular processes. These cell lines are genetically modified to have the STRN3 gene inactivated, allowing researchers to investigate the functional consequences of STRN3 loss in various biological pathways.
The primary function of these knockout cell lines lies in their ability to mimic the phenotypic outcomes observed in organisms with impaired STRN3 expression. STRN3 plays a critical role in cellular signaling and has been implicated in neurodegenerative diseases, making the knockout model particularly useful for elucidating its functions. By utilizing techniques such as CRISPR-Cas9, our STRN3 Gene Knockout Cell Lines are created with high specificity and efficiency, ensuring that researchers can conduct controlled experiments to assess the impacts of STRN3 deficiency on cellular behavior, gene expression, and protein interactions.
The scientific importance of STRN3 Gene Knockout Cell Lines cannot be overstated; they serve as invaluable tools for understanding the molecular mechanisms underpinning diseases where STRN3 is implicated, facilitating the development of targeted therapeutics. Their applications extend to drug screening, mechanistic studies, and biomarker discovery, making them highly relevant in both academic and clinical research settings.
What sets our STRN3 Gene Knockout Cell Lines apart from other options on the market is the quality assurance that comes from our rigorous validation processes. Each line is characterized for successful knockout and validated through multiple assays, including Western blotting and RT-qPCR, ensuring reliable and reproducible results. This commitment to quality enhances the robustness of experimental outcomes, providing greater confidence in research interpretations.
For researchers, clinicians, and biotech companies looking to unravel the complexities of STRN3-related pathologies, our STRN3 Gene Knockout Cell Lines offer a unique and powerful resource. These cell lines not only pave the way for innovative research but also hold great promise for future therapeutic strategies aimed at mitigating the effects of diseases involving STRN3 dysfunction.
Our company brings expertise in producing high-quality biological products tailored to meet the rigorous demands of modern research, ensuring that scientists have access to reliable tools that advance their findings and contribute to groundbreaking discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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