Gene: STMN3
Official Full Name: stathmin 3provided by HGNC
Gene Summary: This gene encodes a protein which is a member of the stathmin protein family. Members of this protein family form a complex with tubulins at a ratio of 2 tubulins for each stathmin protein. Microtubules require the ordered assembly of alpha- and beta-tubulins, and formation of a complex with stathmin disrupts microtubule formation and function. A pseudogene of this gene is located on chromosome 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23263 | STMN3 Knockout cell line (HeLa) | Human | STMN3 | 1:3~1:6 | Negative | Online Inquiry |
KO23264 | STMN3 Knockout cell line (HCT 116) | Human | STMN3 | 1:2~1:4 | Negative | Online Inquiry |
KO23265 | STMN3 Knockout cell line (HEK293) | Human | STMN3 | 1:3~1:6 | Negative | Online Inquiry |
KO23266 | STMN3 Knockout cell line (A549) | Human | STMN3 | 1:3~1:4 | Negative | Online Inquiry |
STMN3 Gene Knockout Cell Lines are genetically engineered cell lines in which the STMN3 gene—known for its role in microtubule dynamics and neuronal development—has been effectively disrupted. This product is an essential tool for researchers aiming to investigate the biological roles of STMN3 in various cellular processes, such as neurogenesis, cell proliferation, and apoptosis. By allowing for the selective ablation of STMN3 expression, these knockout cell lines enable the examination of phenotypic changes and molecular pathways associated with this gene's loss, offering insights into its contribution to neurodegenerative diseases, cancer biology, and other disorders.
The key functions of STMN3 are rooted in its ability to bind to tubulin, facilitating microtubule stabilization, which is critical for maintaining cellular morphology and motility. In research and clinical applications, these knockout cell lines can elucidate the downstream effects of STMN3 dysfunction, allowing scientists to explore its involvement in pathologies such as Alzheimer's or other neurodegenerative conditions. Furthermore, they serve as valuable models for testing potential therapeutic agents that target the pathways affected by STMN3 loss.
Compared to traditional gene silencing methods, STMN3 Gene Knockout Cell Lines offer a more stable and permanent alteration of gene expression, ensuring consistent results across experiments. This can significantly enhance the reliability of experimental outcomes and reduces variability, a common issue associated with transient knockdown techniques. Additionally, the use of completely knock-out models can provide clearer insights into gene function without residual activity that may occur in knockdown scenarios.
The STMN3 Gene Knockout Cell Lines stand out by facilitating deeper, more controlled investigations into the complexities of STMN3-related cellular functions, paving the way for innovative research and potential therapeutic developments. For researchers and clinicians, these cell lines are invaluable for advancing knowledge in both basic and applied biological sciences.
At our company, we specialize in providing high-quality, reliable, and rigorously validated biological products that support cutting-edge research. With our expertise in developing genetically modified cell lines, we are committed to empowering the scientific community with the tools necessary to unlock new discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.