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STMN1 Knockout Cell Lines

Gene: STMN1

Official Full Name: stathmin 1provided by HGNC

Gene Summary: This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO10473 STMN1 Knockout cell line (HeLa) Human STMN1 1:3~1:6 Negative Online Inquiry
KO10474 STMN1 Knockout cell line (HCT 116) Human STMN1 1:2~1:4 Negative Online Inquiry
KO10475 STMN1 Knockout cell line (HEK293) Human STMN1 1:3~1:6 Negative Online Inquiry
KO10476 STMN1 Knockout cell line (A549) Human STMN1 1:3~1:4 Negative Online Inquiry

Background

STMN1 Gene Knockout Cell Lines are genetically modified cell lines designed specifically to lack the expression of the stathmin 1 (STMN1) gene. This gene is known to play a crucial role in the regulation of microtubule dynamics, making it an essential target for research into cell proliferation, differentiation, and apoptosis. These cell lines function by utilizing CRISPR/Cas9 technology, which allows for precise genomic editing and the creation of stable knockout models. As a result, researchers can effectively assess the functional consequences of STMN1 loss, thereby providing insights into various cellular processes and their implications in diseases such as cancer.

The significance of STMN1 Gene Knockout Cell Lines extends to a variety of applications in both basic research and clinical settings. They are particularly valuable in studying the mechanisms underlying tumorigenesis, neurodegenerative diseases, and other conditions where microtubule instability is a factor. By elucidating the pathways influenced by STMN1, these cell lines serve as a vital tool for developing targeted therapies, screening potential drug candidates, and validating therapeutic approaches that involve modulation of microtubule dynamics.

One of the standout advantages of STMN1 Gene Knockout Cell Lines is their ability to provide a highly specific and controlled model for experimentation, minimizing off-target effects common in less sophisticated gene-editing strategies. This precision not only enhances the reproducibility of experimentation but also offers researchers a clearer understanding of STMN1's multifaceted roles. Compared to alternative methods such as RNA interference, these knockout cell lines allow for permanent gene modification, enabling more extensive studies over prolonged periods.

For researchers and clinicians focused on advancing understanding in cellular biology and disease mechanisms, the STMN1 Gene Knockout Cell Lines represent a crucial resource. They bridge the gap between theoretical concepts and practical applications, driving forward scientific discovery and therapeutic innovation. Our company specializes in providing high-quality biological products developed through rigorous protocols and an unwavering commitment to accuracy and reliability. With expertise in genetic engineering, we are dedicated to empowering scientific progress by supplying tools that facilitate groundbreaking research.

Please note that all services are for research use only. Not intended for any clinical use.

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