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STC2 Knockout Cell Lines

Gene: STC2

Official Full Name: stanniocalcin 2provided by HGNC

Gene Summary: This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO02458 STC2 Knockout cell line (HeLa) Human STC2 1:3~1:6 Negative Online Inquiry
KO02459 STC2 Knockout cell line (HCT 116) Human STC2 1:2~1:4 Negative Online Inquiry
KO02460 STC2 Knockout cell line (HEK293) Human STC2 1:3~1:6 Negative Online Inquiry
KO02461 STC2 Knockout cell line (A549) Human STC2 1:3~1:4 Negative Online Inquiry

Background

STC2 Gene Knockout Cell Lines are genetically modified cell cultures designed to facilitate the study of the Stanniocalcin 2 (STC2) gene's functions and its role in various biological processes. These cell lines are characterized by the complete disruption of the STC2 gene, achieved through advanced CRISPR-Cas9 technology, allowing for a precise investigation of the gene's contributions to cellular regulation, metabolism, and disease pathology.

The primary function of STC2 is associated with calcium homeostasis and the regulation of mineral ion levels, crucial for maintaining cellular and systemic balance. By utilizing these knockout cell lines, researchers can elucidate the molecular pathways influenced by STC2, assess its impact on cellular responses to environmental stressors, and explore its potential role in pathologies such as cancer and metabolic disorders. The knockout framework provides an unparalleled opportunity to investigate gene-gene interactions and compensatory mechanisms in experimental settings.

In scientific research and clinical environments, the STC2 Gene Knockout Cell Lines represent a vital tool for functional genomics, enabling the exploration of therapeutic targets and biomarker discovery linked to STC2 dysregulation. These cell lines are invaluable in preclinical studies designed to develop novel treatments, providing insights that could pave the way for innovative therapies.

One of the distinct advantages of our STC2 Gene Knockout Cell Lines over alternative products is their verification of gene disruption through sequencing and functional assays, ensuring the quality and reliability of experimental results. Moreover, our cell lines are optimized for high viability and reproducibility, critical factors for experimental consistency.

For researchers and clinicians alike, these cell lines offer a unique resource for advancing scientific knowledge and driving innovation in therapeutic approaches. Our company brings years of expertise in the field of molecular biology and genetics, ensuring that the STC2 Gene Knockout Cell Lines are not only robust but also supported by a commitment to excellence in biological research products. We are dedicated to providing tools that empower the scientific community to make breakthroughs in understanding complex biological systems.

Please note that all services are for research use only. Not intended for any clinical use.

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