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SPIN4 Knockout Cell Lines

Gene: SPIN4

Official Full Name: spindlin family member 4provided by HGNC

Gene Summary: Enables methylated histone binding activity. Involved in negative regulation of cell population proliferation and positive regulation of canonical Wnt signaling pathway. Located in chromatin; cytoplasm; and nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25822 SPIN4 Knockout cell line (HeLa) Human SPIN4 1:3~1:6 Negative Online Inquiry
KO25823 SPIN4 Knockout cell line (HCT 116) Human SPIN4 1:2~1:4 Negative Online Inquiry
KO25824 SPIN4 Knockout cell line (HEK293) Human SPIN4 1:3~1:6 Negative Online Inquiry
KO25825 SPIN4 Knockout cell line (A549) Human SPIN4 1:3~1:4 Negative Online Inquiry

Background

SPIN4 Gene Knockout Cell Lines are advanced biological tools designed for the precise manipulation of genetic material in cellular systems. These cell lines are engineered using cutting-edge CRISPR-Cas9 technology to specifically disrupt the SPIN4 gene, facilitating the study of its biological function and role in various diseases. By creating stable knockout models, researchers can effectively assess gene function, leading to deeper insights into cellular pathways and mechanisms.

The key function of SPIN4 Gene Knockout Cell Lines lies in their ability to mimic loss-of-function mutations, enabling scientists to explore the downstream effects on gene expression, cellular behavior, and phenotypic changes. The knockout mechanism is executed through targeted homologous recombination or non-homologous end joining, resulting in the permanent inactivation of the target gene. This versatility makes these cell lines an indispensable resource for molecular biology research, therapeutic target validation, and drug development.

From a scientific standpoint, SPIN4 Gene Knockout Cell Lines are pivotal in elucidating the roles of the SPIN4 gene in conditions such as neurodegenerative diseases and cancer. They serve as highly relevant models for screening potential therapeutic agents and understanding the complex interplay between genetic factors and disease phenotypes. In clinical settings, these models support translational research, aiding in the discovery of novel targets for intervention.

The advantages of the SPIN4 Gene Knockout Cell Lines over traditional models include the ease of use, reproducibility, and the ability to generate data that closely reflect in vivo conditions. Unlike transient transfection methods or siRNA approaches that provide temporary knockdown, these cell lines allow for stable and long-lasting gene inactivation. Researchers can leverage these unique selling points to enhance the reliability and impact of their findings.

For researchers and clinicians seeking to advance their understanding of gene function and its implications in disease, SPIN4 Gene Knockout Cell Lines present an invaluable asset. By investing in this product, users gain access to high-quality, rigorously validated models that can significantly streamline their research efforts and contribute to groundbreaking discoveries.

Our company stands at the forefront of biotechnological innovation, specializing in premium research tools tailored to support scientific advancement. With our expertise in gene editing technology and commitment to quality, we strive to empower researchers in their quest for knowledge and therapeutic breakthroughs.

Please note that all services are for research use only. Not intended for any clinical use.

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