Home / SPEF2 Knockout Cell Lines

SPEF2 Knockout Cell Lines

Gene: SPEF2

Official Full Name: sperm flagellar 2provided by HGNC

Gene Summary: Involved in sperm axoneme assembly. Located in sperm flagellum. Implicated in spermatogenic failure 43. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO20723 SPEF2 Knockout cell line (HeLa) Human SPEF2 1:3~1:6 Negative Online Inquiry
KO20724 SPEF2 Knockout cell line (HCT 116) Human SPEF2 1:2~1:4 Negative Online Inquiry
KO20725 SPEF2 Knockout cell line (A549) Human SPEF2 1:3~1:4 Negative Online Inquiry

Background

SPEF2 Gene Knockout Cell Lines are advanced cellular models specifically engineered to investigate the functions of the SPEF2 gene, which plays a crucial role in various biological processes, including cilia formation and cellular motility. These knockout cell lines have been created by employing CRISPR-Cas9 gene-editing technology, resulting in the targeted deletion of the SPEF2 gene, which allows researchers to study the phenotypic consequences of gene loss in a controlled environment.

The key function of these cell lines lies in their ability to simulate disease conditions associated with SPEF2 dysregulation, providing invaluable insights into the gene's role in both normal physiology and disease pathogenesis. By studying the modified cell lines, researchers can elucidate mechanisms underlying cilia-related disorders, such as primary ciliary dyskinesia, which is linked to compromised respiratory function and fertility issues.

Scientifically, the SPEF2 Gene Knockout Cell Lines are exceptionally important for translational research and drug discovery, as they enable the evaluation of potential therapeutic strategies targeting ciliary dysfunction. In clinical settings, understanding the SPEF2 gene's functions can aid the development of novel diagnostic markers and interventions for related diseases.

Compared to traditional cell lines, SPEF2 knockout models provide a more precise platform that mirrors specific genetic alterations, reducing the complexity of data interpretation. This specificity enhances the reliability of results and accelerates the research process.

For researchers and clinicians focusing on genetic disorders, these cell lines represent a unique opportunity to explore gene function and develop promising therapies. Our company is dedicated to providing high-quality biological products, supported by a team of experts in gene editing and cellular biology, ensuring that our customers receive not only the best tools for their research but also the scientific support they need to succeed.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.