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SPATA17 Knockout Cell Lines

Gene: SPATA17

Official Full Name: spermatogenesis associated 17provided by HGNC

Gene Summary: Predicted to enable calmodulin binding activity. Predicted to be involved in establishment of meiotic spindle localization; mitotic cell cycle; and spindle organization. Predicted to be located in cytoplasm. Predicted to be active in spindle pole. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26794 SPATA17 Knockout cell line (HCT 116) Human SPATA17 1:2~1:4 Negative Online Inquiry
KO26795 SPATA17 Knockout cell line (A549) Human SPATA17 1:3~1:4 Negative Online Inquiry

Background

SPATA17 Gene Knockout Cell Lines are genetically engineered cellular models designed to study the function and role of the SPATA17 gene in various biological processes. These cell lines have been developed using advanced CRISPR-Cas9 gene editing technology, resulting in precise and effective depletion of SPATA17 expression. This allows researchers to investigate the gene's involvement in spermatogenesis, fertility, and related molecular pathways, providing insights into its physiological and pathological roles.

Mechanistically, the SPATA17 knockout cell lines facilitate the analysis of loss-of-function phenotypes associated with SPATA17. By observing changes in cellular behavior, signaling pathways, and gene expression profiles in comparison to wild-type control cell lines, scientific investigations can clearly delineate the biological significance of SPATA17. These models can be employed in various assays, including proliferation studies, apoptosis assays, and functional assays pertinent to reproductive biology.

The scientific importance of SPATA17 Gene Knockout Cell Lines extends to both fundamental research and clinical applications. For researchers studying male infertility or genetic disorders related to reproductive health, these models provide a critical tool for understanding the molecular basis of diseases. Additionally, they aid in the development of therapeutic interventions aimed at correcting or compensating for the malfunction of this gene.

One of the noteworthy advantages of our SPATA17 Gene Knockout Cell Lines over traditional models is their high specificity and reproducibility. Unlike other methodologies that involve broader genetic modifications, our cell lines offer a pure knockout without off-target effects, thereby minimizing variables in experimental outcomes. Moreover, they are easily integrated into existing workflows, providing researchers with a straightforward means to advance their studies without extensive setup or troubleshooting.

In summary, SPATA17 Gene Knockout Cell Lines are invaluable to researchers and clinicians alike, enabling a deep exploration of the gene's role in reproductive biology and related fields. By leveraging our expertise in gene editing and cell line development, our company consistently delivers high-quality biological products that empower scientific discovery and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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