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SPACA9 Knockout Cell Lines

Gene: SPACA9

Official Full Name: sperm acrosome associated 9provided by HGNC

Gene Summary: Enables microtubule binding activity. Involved in axoneme assembly. Located in axonemal microtubule. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO31230 SPACA9 Knockout cell line (HeLa) Human SPACA9 1:3~1:6 Negative Online Inquiry
KO31231 SPACA9 Knockout cell line (HCT 116) Human SPACA9 1:2~1:4 Negative Online Inquiry
KO31232 SPACA9 Knockout cell line (HEK293) Human SPACA9 1:3~1:6 Negative Online Inquiry
KO31233 SPACA9 Knockout cell line (A549) Human SPACA9 1:3~1:4 Negative Online Inquiry

Background

SPACA9 Gene Knockout Cell Lines are specialized, genetically modified cell lines designed to specifically eliminate the expression of the SPACA9 gene. These cell lines utilize advanced CRISPR-Cas9 gene-editing technology, producing a deliberate knockout of SPACA9, a gene known to play a crucial role in sperm-egg interactions and fertilization processes. By disabling this gene, researchers can investigate its function and the broader implications it has on reproductive biology, in addition to providing insights into potential infertility issues.

The cell lines' primary mechanism involves the precise and irreversible alteration of the SPACA9 locus, ensuring that researchers have access to a reliable model for studying the gene's in vitro effects. This controlled knockout allows for the examination of downstream signaling pathways and protein interactions that would otherwise be confounded by normal gene expression. Such clarity is invaluable in both academic research and pharmaceutical development, especially in the realms of reproductive health and gene therapy.

The scientific importance of SPACA9 Gene Knockout Cell Lines cannot be overstated, as they serve as a critical resource for elucidating the mechanisms that underpin fertilization and related cellular events. Their application stretches across various research areas, from developmental biology to the creation of innovative therapeutics aimed at treating infertility.

Compared to traditional methods of gene knockdown, such as RNA interference, the SPACA9 Gene Knockout Cell Lines offer a permanent and more reliable solution for gene inactivation. This sustained disruption of the SPACA9 gene provides researchers with consistent data throughout their studies. Additionally, the ease of use and reproducibility of these knockout models streamline experimental workflows, saving valuable time and resources.

For researchers, clinicians, and educators focused on reproductive biology and genetics, investing in SPACA9 Gene Knockout Cell Lines can enhance their understanding of gamete interaction and reproductive viability, ultimately aiding in the development of novel treatments. Our company prides itself on being at the forefront of genetic research tools, consistently delivering high-quality products designed to empower scientific innovation and discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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