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SOX3 Knockout Cell Lines

Gene: SOX3

Official Full Name: SRY-box transcription factor 3provided by HGNC

Gene Summary: This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene have been associated with X-linked cognitive disability with growth hormone deficiency. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO04144 SOX3 Knockout cell line (HEK293) Human SOX3 1:3~1:6 Negative Online Inquiry

Background

SOX3 Gene Knockout Cell Lines are specialized cellular models created by the targeted disruption of the SOX3 gene, which encodes a transcription factor critical for developmental processes, particularly in the nervous system and embryonic development. These cell lines serve as invaluable tools for investigating the role of SOX3 in various biological processes, including stem cell pluripotency, neural differentiation, and the regulation of neuroendocrine functions.

The primary mechanism of action involves the knockout of the SOX3 gene, leading to loss-of-function effects that can highlight the gene's contributions to critical pathways. Researchers utilize these cell lines to explore downstream effects of SOX3 absence, elucidating its involvement in key cellular functions such as apoptosis, proliferation, and differentiation. This functional insight is pivotal for studies related to developmental biology, regenerative medicine, and even cancer research.

In the scientific landscape, SOX3 Gene Knockout Cell Lines have significant applications ranging from basic research to clinical insights. These models provide a platform for drug screening, gene therapy evaluations, and the study of genetic disorders influenced by SOX3 dysregulation. Their utility extends to understanding the molecular underpinnings of diseases such as congenital disorders and various neurodevelopmental conditions.

Compared to traditional cell lines or non-targeted methods, the SOX3 Gene Knockout Cell Lines offer specific advantages: they provide a clean genetic background, enabling more straightforward interpretation of experimental data without confounding variables. The precision of CRISPR/Cas9 technology used to generate these lines ensures high efficiency and specificity in gene targeting, a critical element for researchers aiming to unravel complex biological interactions.

The value of SOX3 Gene Knockout Cell Lines lies in their ability to significantly advance research efforts focused on gene function and its implications in health and disease. They are essential for researchers and clinicians who seek to leverage these models for innovative therapeutic approaches or to gain deeper insights into disease mechanisms.

Our company specializes in providing high-quality biological research products, and with our commitment to precision and excellence, we present these knockout cell lines as reliable resources to empower the scientific community in their pursuit of knowledge and breakthroughs.

Please note that all services are for research use only. Not intended for any clinical use.

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