Home / SOX21 Knockout Cell Lines

SOX21 Knockout Cell Lines

Gene: SOX21

Official Full Name: SRY-box transcription factor 21provided by HGNC

Gene Summary: SRY-related HMG-box (SOX) genes encode a family of DNA-binding proteins containing a 79-amino acid HMG (high mobility group) domain that shares at least 50% sequence identity with the DNA-binding HMG box of the SRY protein (MIM 480000). SOX proteins are divided into 6 subgroups based on sequence similarity within and outside of the HMG domain. For additional background information on SOX genes, see SOX1 (MIM 602148).[supplied by OMIM, Apr 2004]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO31137 SOX21 Knockout cell line (HEK293) Human SOX21 1:3~1:6 Negative Online Inquiry
KO31138 SOX21 Knockout cell line (A549) Human SOX21 1:3~1:4 Negative Online Inquiry

Background

SOX21 Gene Knockout Cell Lines represent a sophisticated tool for researchers investigating the functional roles of the SOX21 gene, a crucial transcription factor implicated in the regulation of neural differentiation and other cellular processes. These cell lines are engineered to ensure precise inactivation of the SOX21 gene, facilitating the exploration of pathways and mechanisms that govern various biological functions, particularly in developmental and cancer biology.

Mechanistically, the SOX21 Gene Knockout Cell Lines leverage CRISPR-Cas9 technology, employing a targeted approach to induce double-strand breaks in the SOX21 locus, leading to frame-shift mutations and subsequent loss of gene function. This method is both efficient and precise, allowing researchers to study the phenotypic changes associated with the absence of SOX21 expression. Such cell lines enable detailed investigations into cellular proliferation, differentiation, and the underlying genetic networks that SOX21 interacts with.

The scientific importance of these cell lines cannot be overstated. They are instrumental in advancing our understanding of SOX21’s role in various physiological and pathological contexts, enhancing drug discovery processes, and developing novel therapeutic strategies. In clinical settings, insights gained from studies using SOX21 knockout models can pave the way for targeted interventions in diseases where SOX21 is misregulated, particularly in different types of cancers.

Compared to conventional knockout methods, SOX21 Gene Knockout Cell Lines provide a time-efficient and cost-effective solution, minimizing off-target effects and maximizing experimental reproducibility. By utilizing these cell lines, researchers can achieve high-throughput results with less variability, which is essential for producing reliable data.

Investing in SOX21 Gene Knockout Cell Lines not only enhances the quality of scientific research but also empowers researchers and clinicians to push the boundaries of genetic exploration. Our company is committed to delivering high-quality biological products backed by extensive expertise in genetic engineering and cell line development, ensuring our clients access to cutting-edge tools necessary for impactful discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.