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SOS2 Knockout Cell Lines

Gene: SOS2

Official Full Name: SOS Ras/Rho guanine nucleotide exchange factor 2provided by HGNC

Gene Summary: This gene encodes a regulatory protein that is involved in the positive regulation of ras proteins. Mutations in this gene are associated with Noonan Syndrome-9. [provided by RefSeq, Jul 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO11158 SOS2 Knockout cell line (HeLa) Human SOS2 1:3~1:6 Negative Online Inquiry
KO11159 SOS2 Knockout cell line (HCT 116) Human SOS2 1:2~1:4 Negative Online Inquiry
KO11160 SOS2 Knockout cell line (HEK293) Human SOS2 1:3~1:6 Negative Online Inquiry
KO11161 SOS2 Knockout cell line (A549) Human SOS2 1:3~1:4 Negative Online Inquiry

Background

SOS2 Gene Knockout Cell Lines represent a significant advancement in molecular biology that allows researchers to study the functions of the SOS2 gene without the influence of its encoded protein. These cell lines are meticulously engineered using CRISPR/Cas9 gene-editing technology, resulting in a complete knockout of the SOS2 gene, which plays a crucial role in signaling pathways that regulate cell growth, differentiation, and survival in various tissues. By removing SOS2, researchers can delve into the gene’s specific contributions to cellular mechanisms and its broader implications in oncogenesis and developmental biology.

The key functions of SOS2 have been linked to its role as a guanine nucleotide exchange factor (GEF) that activates RAS proteins, crucial for cell signaling pathways. The SOS2 Gene Knockout Cell Lines facilitate the study of RAS-related pathways, enabling the evaluation of therapeutic targets and the understanding of drug resistance in cancer treatments. This product is particularly valuable in research settings where elucidating the pathophysiology of diseases is essential for developing innovative treatments.

One of the standout advantages of the SOS2 Gene Knockout Cell Lines is their precision in gene editing, which is superior to traditional knockout models that may introduce off-target effects. This high specificity enhances the reliability of experimental results, garnering greater confidence for researchers in their findings. Additionally, maintaining consistency in cell line characteristics over time reduces variability, allowing for reproducible experiments across different laboratories.

Researchers and clinicians who utilize SOS2 Gene Knockout Cell Lines find them to be invaluable tools for dissecting complex biological pathways. Their application extends to drug discovery, functional genomics, and personalized medicine, bridging critical gaps in our understanding of gene function in disease.

Our company prides itself on extensive expertise in genetic engineering and cell line development, ensuring that our products meet rigorous scientific standards and contribute to advancing research in molecular and cellular biology. With our SOS2 Gene Knockout Cell Lines, we empower researchers to unlock new insights into gene function and disease mechanisms.

Please note that all services are for research use only. Not intended for any clinical use.

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