Home / SOCS5 Knockout Cell Lines

SOCS5 Knockout Cell Lines

Gene: SOCS5

Official Full Name: suppressor of cytokine signaling 5provided by HGNC

Gene Summary: The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported. [provided by RefSeq, Jul 2008]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO11174 SOCS5 Knockout cell line (HeLa) Human SOCS5 1:3~1:6 Negative Online Inquiry
KO11175 SOCS5 Knockout cell line (HCT 116) Human SOCS5 1:2~1:4 Negative Online Inquiry
KO11176 SOCS5 Knockout cell line (HEK293) Human SOCS5 1:3~1:6 Negative Online Inquiry
KO11177 SOCS5 Knockout cell line (A549) Human SOCS5 1:3~1:4 Negative Online Inquiry

Background

SOCS5 Gene Knockout Cell Lines are genetically engineered cell lines in which the Suppressor of Cytokine Signaling 5 (SOCS5) gene has been specifically deleted. This modification allows for the in-depth study of the SOCS5 protein's role in various cellular processes, particularly those linked to immune response regulation, cell proliferation, and differentiation. By knocking out this gene, researchers are provided with a powerful tool to examine the mechanistic pathways that are influenced by SOCS5, thus facilitating a clearer understanding of its functional significance within complex biological systems.

The key function of SOCS5 lies in its role as a feedback inhibitor of cytokine signaling, which plays a critical part in the immune response. Through its action, SOCS5 modulates the activity of various signaling pathways, including the JAK/STAT pathway, which is crucial for cell signaling related to immune function and hematopoiesis. With the SOCS5 knockout, researchers can observe aberrations in these signaling cascades, leading to insights that could influence both basic and translational research.

The scientific importance of SOCS5 Gene Knockout Cell Lines extends to numerous applications in research settings, including understanding autoimmune diseases, inflammatory responses, and tumor biology. Furthermore, in clinical settings, these cell models hold the potential for developing targeted therapies that could manipulate SOCS5 signaling pathways to afford therapeutic advantage against certain cancers and immune disorders.

One distinctive advantage of SOCS5 Gene Knockout Cell Lines over traditional models is the precise gene editing achieved through CRISPR/Cas9 technology, which ensures a high fidelity of gene deletion. This meticulous approach yields reproducible and robust results, making these cell lines ideal for longitudinal studies. Additionally, as they are pre-established and commercially available, they save valuable time and resources for researchers who would otherwise invest considerable effort into creating their knockout models.

Researchers, clinicians, and biotech professionals will find invaluable insights within these cell lines, enhancing the understanding of disease pathways and accelerating the development of innovative therapeutic strategies. By integrating our cutting-edge genetic engineering expertise with a commitment to high-quality biological products, we deliver unparalleled resources that empower your research endeavors, facilitating advancements in life sciences and therapeutic design.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.