Gene: SNX11
Official Full Name: sorting nexin 11provided by HGNC
Gene Summary: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members. This gene encodes a protein of unknown function. This gene results in two transcript variants differing in the 5' UTR, but encoding the same protein. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26948 | SNX11 Knockout cell line (HeLa) | Human | SNX11 | 1:3~1:6 | Negative | Online Inquiry |
KO26949 | SNX11 Knockout cell line (HCT 116) | Human | SNX11 | 1:2~1:4 | Negative | Online Inquiry |
KO26950 | SNX11 Knockout cell line (HEK293) | Human | SNX11 | 1:3~1:6 | Negative | Online Inquiry |
KO26951 | SNX11 Knockout cell line (A549) | Human | SNX11 | 1:3~1:4 | Negative | Online Inquiry |
SNX11 Gene Knockout Cell Lines are specifically engineered cellular models that utilize targeted genome editing techniques to inactivate the SNX11 gene, which is implicated in various cellular processes including endosomal sorting and intracellular trafficking. By employing CRISPR/Cas9 technology or related methods, these knockout cell lines allow researchers to dissect the functional role of SNX11 by observing phenotypic changes that arise due to its absence, thereby providing insights into its biological implications.
The primary mechanism of action involves the deletion or modification of the SNX11 gene, which leads to the disruption of protein synthesis. This results in cells that lack the specific pathways associated with SNX11, making it an invaluable tool for investigating the pathways associated with cellular mobility, signaling, and potential implications in diseases such as cancer or neurodegenerative disorders. Researchers can utilize these cell lines to elucidate the molecular mechanisms underscoring disease states and to identify potential therapeutic targets.
The scientific importance of SNX11 Gene Knockout Cell Lines is evident in their diverse applications in research settings, particularly in studies focused on cellular biology, molecular genetics, and therapeutic drug discovery. Unlike conventional cell lines, the knockout lines provide a controlled model to assess the functional consequences of gene loss, allowing for more accurate descriptions of gene functionality.
One of the defining advantages of our SNX11 Gene Knockout Cell Lines over other alternatives lies in their specificity and reproducibility. Each cell line is meticulously developed and validated for consistent performance, ensuring that researchers can trust the data derived from experiments using these models. Furthermore, our product is supported by comprehensive technical data and protocols, empowering scientists to achieve reliable and reproducible results in their research endeavors.
In conclusion, SNX11 Gene Knockout Cell Lines represent a critical resource for advancing our understanding of SNX11-related signaling and pathology. Backed by our company’s expertise in genetic engineering and commitment to high-quality biological products, we are dedicated to supporting researchers and clinicians in their pursuit of innovative solutions to complex biological challenges.
Please note that all services are for research use only. Not intended for any clinical use.
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