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SNORD48 Knockout Cell Lines

Gene: SNORD48

Official Full Name: small nucleolar RNA, C/D box 48provided by HGNC

Gene Summary: Predicted to be involved in RNA processing. Predicted to be located in nucleolus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00867 SNORD48 Knockout cell line(PC-3) Human SNORD48 1:3~1:4 Negative Online Inquiry

Background

SNORD48 Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to study the functional implications of the SNORD48 gene within various biological contexts. These cell lines have been meticulously crafted through CRISPR-Cas9 technology to facilitate a comprehensive analysis of SNORD48's role in RNA processing and gene regulation. By disrupting the endogenous SNORD48 gene, researchers can investigate the downstream effects on ribosomal RNA maturation and its potential involvement in diseases such as cancer and developmental disorders.

The primary mechanism by which SNORD48 functions involves its role as a small nucleolar RNA (snoRNA), which guides the modification and processing of ribosomal RNA (rRNA). The SNORD48 knockout allows for the elucidation of its specific contributions to the assembly of ribosomes and the regulation of gene expression. This product serves as a crucial tool for scientists seeking to unravel complex cellular processes and the pathophysiology associated with aberrations in snoRNA function.

In the realm of scientific research, the SNORD48 Gene Knockout Cell Lines hold immense significance. They provide a novel platform for the study of ribosome biogenesis dysfunction, enabling clinicians and researchers to explore therapeutic targets for RNA-centric diseases. These cell lines can be employed in high-throughput screening assays, drug discovery, and gene therapy development.

One key advantage of our SNORD48 Gene Knockout Cell Lines is their high reproducibility and specificity, setting them apart from traditional methods that may introduce off-target effects. By utilizing a fully characterized knockout model, users can ensure the reliability of their data, paving the way for breakthroughs in understanding gene regulation.

For researchers and clinicians focused on the intricacies of genetic regulation and its implications in health and disease, the SNORD48 Gene Knockout Cell Lines represent a valuable asset. They embody our commitment to advancing molecular biology by providing high-quality research tools engineered from experience and rigorous scientific inquiry.

With a legacy of excellence in providing innovative biological products, our company is dedicated to supporting the scientific community by equipping them with advanced cellular models that drive impactful discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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