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SNCG Knockout Cell Lines

Gene: SNCG

Official Full Name: synuclein gammaprovided by HGNC

Gene Summary: This gene encodes a member of the synuclein family of proteins which are believed to be involved in the pathogenesis of neurodegenerative diseases. Mutations in this gene have also been associated with breast tumor development. [provided by RefSeq, Jan 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO35330 SNCG Knockout cell line (HeLa) Human SNCG 1:3~1:6 Negative Online Inquiry
KO35331 SNCG Knockout cell line (HCT 116) Human SNCG 1:2~1:4 Negative Online Inquiry
KO35332 SNCG Knockout cell line (HEK293) Human SNCG 1:3~1:6 Negative Online Inquiry
KO35333 SNCG Knockout cell line (A549) Human SNCG 1:3~1:4 Negative Online Inquiry

Background

SNCG Gene Knockout Cell Lines represent a pivotal advancement in the field of molecular biology and genetic research. These cell lines have been specifically engineered to lack the expression of the Synuclein Gamma (SNCG) gene, which has been implicated in a variety of neurodegenerative diseases and cancers. By utilizing CRISPR-Cas9 technology, our SNCG gene knockout cell lines allow researchers to investigate the functional consequences of the absence of SNCG at both cellular and molecular levels.

The primary functions of these knockout cell lines include elucidating the biological role of SNCG in different cellular processes, such as apoptosis, proliferation, and cell signaling. The precise modulation of SNCG gene expression enables researchers to study its effects in vitro, facilitating the development of therapeutic strategies aimed at restoring normal cellular function in affected tissues. Furthermore, the ability to create stable cell lines means consistent data can be obtained, enhancing experimental reproducibility and reliability.

Scientific importance is evident as these knockout models are invaluable in the exploration of SNCG’s role in neurodegenerative disorders, such as Alzheimer's and Parkinson's diseases, as well as in various types of cancers where SNCG overexpression is noted. By employing these models, researchers can identify potential biomarkers or therapeutic targets, potentially paving the way for innovative treatment methodologies.

Compared to traditional methods of gene modification, our SNCG Gene Knockout Cell Lines offer several distinct advantages. The precision of CRISPR technology minimizes off-target effects, leading to a more accurate reflection of SNCG's biological role. Additionally, our cell lines come pre-validated and are ready for immediate use, significantly reducing the time and resources spent on gene editing procedures.

For researchers and clinicians, the value of using SNCG Gene Knockout Cell Lines lies in their ability to accelerate findings in complex biological systems and contribute to advancing therapeutic interventions. Understanding SNCG’s functions can lead to breakthroughs that are critical in managing and potentially treating conditions characterized by its dysregulation.

At [Your Company Name], we pride ourselves on our commitment to providing high-quality, innovative biological products. With an expert team dedicated to supporting the research community, our SNCG Gene Knockout Cell Lines embody our mission to enable scientific discovery and enhance therapeutic advancements.

Please note that all services are for research use only. Not intended for any clinical use.

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