Gene: SNAPIN
Official Full Name: SNAP associated proteinprovided by HGNC
Gene Summary: The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis of lysosome-related organelles) complex. Biochemical studies have identified additional binding partners. As part of the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1 complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules. Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO04229 | SNAPIN Knockout cell line (HeLa) | Human | SNAPIN | 1:3~1:6 | Negative | Online Inquiry |
KO04230 | SNAPIN Knockout cell line (HCT 116) | Human | SNAPIN | 1:2~1:4 | Negative | Online Inquiry |
KO04231 | SNAPIN Knockout cell line (HEK293) | Human | SNAPIN | 1:3~1:6 | Negative | Online Inquiry |
KO04232 | SNAPIN Knockout cell line (A549) | Human | SNAPIN | 1:3~1:4 | Negative | Online Inquiry |
SNAPIN Gene Knockout Cell Lines are a suite of genetically engineered cell lines that have been meticulously crafted to facilitate research in gene function, disease modeling, and drug discovery. Utilizing the advanced CRISPR-Cas9 genome editing technology, these cell lines enable precise and efficient deletion of target genes, allowing researchers to investigate the implications of specific gene loss on cellular pathways and phenotypes.
The key function of SNAPIN Gene Knockout Cell Lines lies in their ability to unveil the roles of targeted genes in both normal and pathological states. By knocking out genes implicated in various diseases, these cell lines serve as vital tools for understanding gene function and the underlying mechanisms driving conditions such as cancer, neurodegenerative disorders, and metabolic syndromes. The knockout approach provides a clear advantage in discerning the functional consequences of gene inactivation, as opposed to knockdown techniques that may leave residual gene expression.
The scientific importance of these products is underscored by their broad applications in both basic and translational research. Researchers can use SNAPIN Gene Knockout Cell Lines to elucidate disease mechanisms, identify potential therapeutic targets, and test novel drug candidates in a controlled environment that closely resembles in vivo conditions.
Compared to traditional gene knockdown methods, SNAPIN Gene Knockout Cell Lines offer more stable, permanent gene modifications, leading to more reliable and reproducible data. They are optimized for key areas of study, including functional genomics, toxicology, and regenerative medicine, ensuring that users can derive meaningful insights from their experimental outcomes.
For researchers and clinicians striving to push the boundaries of scientific discovery, the reliability and precision of SNAPIN Gene Knockout Cell Lines make them an invaluable asset in any laboratory. This product empowers users with the ability to contribute to significant advancements in understanding gene function and developing novel therapeutic approaches.
Our company prides itself on being at the forefront of genetic engineering and biotechnology, offering exceptional products that cater to the evolving needs of the scientific community. With our expertise, we are committed to delivering high-quality tools that ignite innovation in research and clinical applications.
Please note that all services are for research use only. Not intended for any clinical use.
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