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SNAI2 Knockout Cell Lines

Gene: SNAI2

Official Full Name: snail family transcriptional repressor 2provided by HGNC

Gene Summary: This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO08486 SNAI2 Knockout cell line (HeLa) Human SNAI2 1:3~1:6 Negative Online Inquiry
KO08487 SNAI2 Knockout cell line (HEK293) Human SNAI2 1:3~1:6 Negative Online Inquiry
KO08488 SNAI2 Knockout cell line (A549) Human SNAI2 1:3~1:4 Negative Online Inquiry

Background

SNAI2 Gene Knockout Cell Lines represent a cutting-edge tool for researchers focused on elucidating the role of the SNAI2 gene in various biological processes, particularly in cellular development and differentiation. These cell lines are genetically engineered to have a complete deletion of the SNAI2 gene, facilitating the study of its functions in a controlled environment.

The primary mechanism of the SNAI2 knockout relies on the CRISPR-Cas9 gene-editing technology, which allows for precise targeting and disruption of the SNAI2 gene. By inhibiting the function of SNAI2, a transcription factor associated with epithelial-mesenchymal transition (EMT) and cellular migration, researchers can investigate the downstream effects on cell behavior, gene expression, and the molecular pathways involved in various diseases, including cancer and fibrosis.

The scientific importance of SNAI2 Gene Knockout Cell Lines is underscored by their applications in research settings that aim to dissect the complex mechanisms of cellular communication and morphogenesis. In clinical contexts, insights gained from these cell lines can lead to the development of targeted therapies for conditions where SNAI2 plays a critical role, thereby expanding therapeutic options for patients.

What sets our SNAI2 Gene Knockout Cell Lines apart from traditional models is their high efficiency and specificity, providing researchers with reliable and reproducible results. Unlike wild-type cell lines, these knockouts enable clear observations of the consequences of SNAI2 loss, allowing for detailed studies on cellular pathways without the confounding effects of gene expression variability.

For researchers and clinicians alike, the value of utilizing SNAI2 Gene Knockout Cell Lines lies in their potential to accelerate discoveries in gene function and therapeutic development. With our expertise in genetic engineering and cell line development, we are committed to providing high-quality, validated products that empower scientific advancements and foster innovation in biological research.

Please note that all services are for research use only. Not intended for any clinical use.

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