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SMTN Knockout Cell Lines

Gene: SMTN

Official Full Name: smoothelinprovided by HGNC

Gene Summary: This gene encodes a structural protein that is found exclusively in contractile smooth muscle cells. It associates with stress fibers and constitutes part of the cytoskeleton. This gene is localized to chromosome 22q12.3, distal to the TUPLE1 locus and outside the DiGeorge syndrome deletion. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO35402 SMTN Knockout cell line (HeLa) Human SMTN 1:3~1:6 Negative Online Inquiry
KO35403 SMTN Knockout cell line (HCT 116) Human SMTN 1:2~1:4 Negative Online Inquiry
KO35404 SMTN Knockout cell line (HEK293) Human SMTN 1:3~1:6 Negative Online Inquiry
KO35405 SMTN Knockout cell line (A549) Human SMTN 1:3~1:4 Negative Online Inquiry

Background

SMTN Gene Knockout Cell Lines represent a significant advancement in genetic research, specifically designed to facilitate the study of gene function and gene-targeted therapies. These cell lines have been established through a precisely designed genome editing process, typically using CRISPR/Cas9 technology, which allows for the targeted disruption of the SMTN gene within the cellular genome. By knocking out this specific gene, researchers can assess the resultant phenotypic changes and elucidate the role that SMTN plays within cellular pathways and disease mechanisms.

The primary function of SMTN Gene Knockout Cell Lines lies in their utility for functional genomics, where understanding gene expression and regulation is paramount. With the knockout of the SMTN gene, studies can be executed to explore pathways related to cell differentiation, proliferation, and response to therapeutic agents. Researchers can utilize these unique cell lines to investigate the role of SMTN in various physiological states, making them invaluable for cancer, metabolic, and neurological research.

The scientific importance of these cell lines is underscored by their application in both preclinical research and drug development. Their ability to provide insights into disease mechanisms can lead to novel therapeutic targets and enhance our understanding of diseases driven by genetic mutations. Moreover, the precise knockout of SMTN allows for reproducibility and high specificity, which is essential in experimental research.

Compared to alternative models, SMTN Gene Knockout Cell Lines offer distinct advantages, including enhanced genetic fidelity, reduced off-target effects, and a streamlined characterization process. These attributes make them superior tools for elucidating complex biological processes as opposed to traditional models that may not accurately recapitulate the genetic disruptions of interest.

For researchers and clinicians, the value of SMTN Gene Knockout Cell Lines lies in their ability to provide high-resolution insights into genetic function, paving the way for innovative discoveries that can translate into clinical applications. Their robustness and specificity afford users a greater understanding of targeted therapies and biomarker development.

Our company specializes in the production and optimization of biological products tailored for cutting-edge research, ensuring that scientists have access to high-quality, reproducible, and relevant cellular models to advance their work.

Please note that all services are for research use only. Not intended for any clinical use.

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