Gene: SMIM19
Official Full Name: small integral membrane protein 19provided by HGNC
Gene Summary: Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30676 | SMIM19 Knockout cell line (HeLa) | Human | SMIM19 | 1:3~1:6 | Negative | Online Inquiry |
KO30677 | SMIM19 Knockout cell line (HCT 116) | Human | SMIM19 | 1:2~1:4 | Negative | Online Inquiry |
KO30678 | SMIM19 Knockout cell line (HEK293) | Human | SMIM19 | 1:3~1:6 | Negative | Online Inquiry |
KO30679 | SMIM19 Knockout cell line (A549) | Human | SMIM19 | 1:3~1:4 | Negative | Online Inquiry |
SMIM19 Gene Knockout Cell Lines are engineered cellular models specifically designed to elucidate the biological functions and pathways associated with the SMIM19 gene. This gene, which encodes a small integral membrane protein, plays critical roles in various cellular processes, including cell proliferation, differentiation, and apoptosis. By utilizing CRISPR-Cas9 technology, these cell lines exhibit a targeted knockout of the SMIM19 gene, allowing for the evaluation of its functional significance in cellular and molecular biology studies.
The mechanism underpinning the SMIM19 knockout is quite sophisticated; the CRISPR-Cas9 system introduces double-strand breaks at specific SMIM19 loci, facilitating gene disruption. Researchers can thus assess the resultant phenotypic changes, providing invaluable insights into the gene’s contribution to specific disease models, particularly in cancer and metabolic disorders.
The scientific importance of SMIM19 Gene Knockout Cell Lines extends to their wide-ranging applications in basic research, drug development, and therapeutic advancements. These cell lines enable researchers to explore the underlying molecular mechanisms of diseases, test new therapeutic interventions, and bridge the gap between cellular assays and in vivo studies.
Compared to traditional methods of gene knockout, such as homologous recombination, these cell lines offer several advantages, including increased efficiency, reduced time to results, and enhanced precision in gene editing. The specificity of CRISPR-Cas9 minimizes off-target effects, thereby providing more reliable data.
For researchers and clinicians, the SMIM19 Gene Knockout Cell Lines represent an essential tool for advancing our understanding of gene function and its implications in health and disease. Their usage can lead to better-targeted therapies and improved patient outcomes.
At [Your Company Name], we pride ourselves on our expertise and commitment to providing high-quality biological products. Our dedication to innovation and scientific rigor ensures that our offerings, like the SMIM19 Gene Knockout Cell Lines, meet the evolving needs of the research community, driving advancements in biomedical science.
Please note that all services are for research use only. Not intended for any clinical use.
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