Home / SMCR8 Knockout Cell Lines

SMCR8 Knockout Cell Lines

Gene: SMCR8

Official Full Name: SMCR8-C9orf72 complex subunitprovided by HGNC

Gene Summary: Enables GTPase activator activity; protein kinase binding activity; and protein kinase inhibitor activity. Contributes to guanyl-nucleotide exchange factor activity. Involved in negative regulation of gene expression; regulation of TOR signaling; and regulation of macroautophagy. Located in Atg1/ULK1 kinase complex; chromatin; and nucleoplasm. Part of guanyl-nucleotide exchange factor complex. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25542 SMCR8 Knockout cell line (HeLa) Human SMCR8 1:3~1:6 Negative Online Inquiry
KO25543 SMCR8 Knockout cell line (HCT 116) Human SMCR8 1:2~1:4 Negative Online Inquiry
KO25544 SMCR8 Knockout cell line (HEK293) Human SMCR8 1:3~1:6 Negative Online Inquiry
KO25545 SMCR8 Knockout cell line (A549) Human SMCR8 1:3~1:4 Negative Online Inquiry

Background

SMCR8 Gene Knockout Cell Lines are specialized cell culture systems engineered to lack the expression of the SMCR8 gene, a critical component in various cellular pathways linked to immune responses and metabolism. These cell lines have been meticulously developed using CRISPR/Cas9 gene-editing technology, ensuring precise and efficient disruption of the targeted gene. As a result, researchers gain valuable tools for elucidating the biological role of SMCR8 in both normal and pathological conditions, enabling the study of its function in processes such as viral infection, cellular stress response, and autophagy.

The key mechanism by which SMCR8 Gene Knockout Cell Lines operate revolves around the complete absence of SMCR8 protein, facilitating direct studies on its interactions with associated molecular partners and pathways. This allows for the exploration of therapeutic targets and the development of new pharmacological agents in contexts such as cancer and autoimmune diseases. The significance of these cell lines in research is profound; they provide a reliable model for understanding the implications of SMCR8 in disease mechanisms, thus paving the way for advancements in treatment strategies.

Compared to conventional knockout models, SMCR8 Gene Knockout Cell Lines offer several distinct advantages. The rapid generation and high specificity of the CRISPR/Cas9 approach ensure minimal off-target effects and a high level of reproducibility, which are crucial for reliable experimental outcomes. Furthermore, these cell lines can be effortlessly integrated into various assays ranging from basic biological research to high-throughput screening, making them versatile tools for any laboratory.

For researchers and clinicians seeking to demystify the roles of gene expression in health and disease, SMCR8 Gene Knockout Cell Lines present an indispensable asset. Their utilization can drive innovations in research, leading to significant breakthroughs in understanding complex biological processes and facilitating the translation of findings into clinical applications.

At our company, we are dedicated to advancing the frontiers of genetic research and provide cutting-edge biological tools like the SMCR8 Gene Knockout Cell Lines, reinforced by our commitment to quality and innovation in the life sciences sector.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.