Gene: SMAP1
Official Full Name: small ArfGAP 1provided by HGNC
Gene Summary: The protein encoded by this gene is similar to the mouse stromal membrane-associated protein-1. This similarity suggests that this human gene product is also a type II membrane glycoprotein involved in the erythropoietic stimulatory activity of stromal cells. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO13967 | SMAP1 Knockout cell line (HeLa) | Human | SMAP1 | 1:3~1:6 | Negative | Online Inquiry |
KO13968 | SMAP1 Knockout cell line (HCT 116) | Human | SMAP1 | 1:2~1:4 | Negative | Online Inquiry |
KO13969 | SMAP1 Knockout cell line (HEK293) | Human | SMAP1 | 1:3~1:6 | Negative | Online Inquiry |
KO13970 | SMAP1 Knockout cell line (A549) | Human | SMAP1 | 1:3~1:4 | Negative | Online Inquiry |
SMAP1 Gene Knockout Cell Lines are genetically engineered cell populations in which the SMAP1 gene has been selectively inactivated, providing a powerful tool for researchers studying the biological roles of this gene in various cellular processes. These cell lines allow scientists to investigate the effects of SMAP1 deficiency on cell behavior, signaling pathways, and gene expression, offering insights into its contributions to cellular functions and disease mechanisms.
The primary function of SMAP1 involves regulating membrane trafficking and cellular signaling by facilitating the transport of proteins through endosomal compartments. By using these knockout cell lines, researchers can elucidate the specific roles of SMAP1 in vesicle formation, nutrient uptake, and cellular responses to environmental stimuli. Such research has implications for understanding diseases where these processes are disrupted, including cancer, metabolic disorders, and neurodegenerative conditions.
The scientific importance of SMAP1 Gene Knockout Cell Lines lies in their ability to serve as model systems for studies utilizing techniques like CRISPR genome editing, pharmacological assays, and morphometric analyses. These applications contribute to both fundamental science and translational research, providing a platform for drug discovery and development.
Compared to conventional gene silencing methods, such as RNA interference, SMAP1 Gene Knockout Cell Lines offer a more stable and permanent alteration, allowing for prolonged studies of gene function without the variability associated with transient knockdown. Their high fidelity and reproducibility enhance the robustness of experimental outcomes, making them an invaluable resource for researchers and clinicians alike.
Investing in SMAP1 Gene Knockout Cell Lines allows researchers to unlock new discoveries and therapeutic strategies, ultimately advancing our understanding of complex biological systems. Our company, with its deep expertise in genetic engineering and commitment to delivering high-quality bioresearch tools, ensures that these cell lines are available for researchers determined to push the boundaries of scientific knowledge in their fields.
Please note that all services are for research use only. Not intended for any clinical use.
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