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SLIRP Knockout Cell Lines

Gene: SLIRP

Official Full Name: SRA stem-loop interacting RNA binding proteinprovided by HGNC

Gene Summary: Steroid receptor RNA activator (SRA, or SRA1; MIM 603819) is a complex RNA molecule containing multiple stable stem-loop structures that functions in coactivation of nuclear receptors. SLIRP interacts with stem-loop structure-7 of SRA (STR7) and modulates nuclear receptor transactivation (Hatchell et al., 2006 [PubMed 16762838]).[supplied by OMIM, Mar 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25601 SLIRP Knockout cell line (HeLa) Human SLIRP 1:3~1:6 Negative Online Inquiry
KO25602 SLIRP Knockout cell line (HCT 116) Human SLIRP 1:2~1:4 Negative Online Inquiry
KO25603 SLIRP Knockout cell line (HEK293) Human SLIRP 1:3~1:6 Negative Online Inquiry
KO25604 SLIRP Knockout cell line (A549) Human SLIRP 1:3~1:4 Negative Online Inquiry

Background

SLIRP Gene Knockout Cell Lines represent a cutting-edge biological tool designed for the exploration of gene function and regulation in mammalian systems. These genetically-engineered cell lines are created by the targeted disruption of the SLIRP gene, which is known to play a crucial role in various cellular processes, including RNA metabolism and gene expression regulation. The knockout strategy allows researchers to study the implications of SLIRP deficiency, enabling insights into its contributions to cellular pathways, disease mechanisms, and potential therapeutic targets.

The key function of SLIRP Gene Knockout Cell Lines lies in their ability to facilitate controlled studies on gene knockdown effects. Researchers can utilize these cell lines to elucidate the role of SLIRP in cellular signaling and metabolism by comparing gene expression profiles and physiological responses between knockout and wild-type cells. This mechanistic understanding can be pivotal for discovering molecular pathways involved in pathological conditions such as cancer and neurodegenerative diseases.

In a research or clinical setting, SLIRP Gene Knockout Cell Lines have significant implications. They serve as powerful models for drug discovery, offering a means to evaluate compound efficacy and mechanism of action in contexts where SLIRP is relevant. Additionally, these cell lines can be leveraged for high-throughput screening to identify small molecules that can modulate gene pathways, expanding therapeutic options for various diseases.

What sets SLIRP Gene Knockout Cell Lines apart from alternative models is their specificity and reliability. Developed under stringent conditions, these cell lines offer consistent genetic integrity and performance. Researchers can depend on these tools to yield reproducible results, reducing variability in experimental outcomes and enhancing data quality.

The value of SLIRP Gene Knockout Cell Lines extends beyond mere experimentation; they empower researchers and clinicians to accelerate their discoveries, fostering innovative solutions in gene therapy and precision medicine. The integration of this product into a laboratory workflow not only simplifies complex genetic studies but also paves the way for new therapeutic strategies.

Our company is dedicated to providing high-quality biological products that support groundbreaking research. With a strong foundation in genetic engineering and cell line development, we ensure that our offerings, including SLIRP Gene Knockout Cell Lines, meet the rigorous demands of modern scientific investigations, contributing to advancements in understanding gene function and disease pathology.

Please note that all services are for research use only. Not intended for any clinical use.

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