Gene: SLCO5A1
Official Full Name: solute carrier organic anion transporter family member 5A1provided by HGNC
Gene Summary: Predicted to enable sodium-independent organic anion transmembrane transporter activity. Predicted to be involved in sodium-independent organic anion transport. Located in intracellular membrane-bounded organelle and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25655 | SLCO5A1 Knockout cell line (HEK293) | Human | SLCO5A1 | 1:3~1:6 | Negative | Online Inquiry |
SLCO5A1 Gene Knockout Cell Lines are specialized cellular models engineered to specifically eliminate the expression of the SLCO5A1 gene. This gene encodes a member of the solute carrier family, which is vital for mediating the transport of a variety of organic compounds, including endogenous metabolites and pharmacological agents, across cellular membranes. The knockout of SLCO5A1 allows researchers to investigate the role of this transporter in various biological processes and disease states, providing insights into its contribution to drug efficacy and metabolism.
The mechanisms by which these knockout cell lines function include the use of advanced CRISPR/Cas9 gene-editing technology, allowing for precise and efficient disruption of the SLCO5A1 gene. This results in a significant reduction or complete absence of the protein product, enabling scientists to observe the resulting phenotypic changes and molecular interactions. Such models are essential for elucidating the physiological and pathological roles of SLCO5A1, particularly in cancer biology, pharmacology, and toxicology.
From a scientific standpoint, SLCO5A1 Gene Knockout Cell Lines are invaluable in both research and clinical settings. They facilitate the identification of the implications of SLCO5A1 in pharmacokinetics and drug response, serving as powerful tools for drug development and personalized medicine. By providing a controlled environment to study gene function, these cell lines empower researchers to derive data that can lead to innovations in therapeutics and diagnostics.
What sets SLCO5A1 Gene Knockout Cell Lines apart from alternative models is their specificity and precision. Unlike traditional knockdown methods, which may leave residual gene expression, these lines ensure complete gene disruption, thereby providing more definitive results. Additionally, our product is supported by comprehensive validation studies, offering robust reliability for experimental reproducibility.
For researchers and clinicians aiming to deepen their understanding of drug transport mechanisms and their impact on health and disease, SLCO5A1 Gene Knockout Cell Lines represent a critical asset. They bridge the gap between basic research and clinical application, assisting in the translation of laboratory findings into meaningful health advancements. Our company, with a longstanding commitment to excellence in genetic engineering and a portfolio of high-quality biological products, ensures that you have access to the most reliable and cutting-edge tools for your research needs.
Please note that all services are for research use only. Not intended for any clinical use.
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