Gene: SLCO2B1
Official Full Name: solute carrier organic anion transporter family member 2B1provided by HGNC
Gene Summary: This locus encodes a member of the organic anion-transporting polypeptide family of membrane proteins. The protein encoded by this locus may function in regulation of placental uptake of sulfated steroids. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO06750 | SLCO2B1 Knockout cell line (HeLa) | Human | SLCO2B1 | 1:3~1:6 | Negative | Online Inquiry |
KO06751 | SLCO2B1 Knockout cell line (A549) | Human | SLCO2B1 | 1:3~1:4 | Negative | Online Inquiry |
SLCO2B1 Gene Knockout Cell Lines are meticulously developed cellular systems designed to provide researchers with a powerful tool for investigating the biological role of the SLCO2B1 gene, which encodes the organic anion transporting polypeptide 2B1 (OATP2B1). This gene plays a crucial role in the intracellular uptake of various endogenous compounds and pharmaceutical drugs, thus influencing pharmacokinetics, drug efficacy, and toxicity.
The primary function of these knockout cell lines is to enable the study of the gene’s role by observing the biological and biochemical changes that occur when SLCO2B1 is absent. Researchers can utilize these cell lines to delineate pathways impacted by the lack of OATP2B1, enhancing our understanding of drug transport mechanisms and their implications in diverse physiological and pathological conditions. This knowledge is invaluable for drug development, helping to improve therapeutic strategies and tailor medications for specific patient populations based on their genetic predispositions.
In comparison to other model systems, SLCO2B1 Gene Knockout Cell Lines present distinct advantages, particularly their specificity and precision in mimicking human cellular conditions. This specificity allows scientists to generate more relevant data regarding drug interactions and transport mechanisms compared to traditional cell lines that may express the SLCO2B1 gene.
For researchers and clinicians alike, the availability of these specialized cell lines is invaluable for advancing drug discovery and understanding individual variations in drug response. By using these models, scientists can engage in translational research that bridges laboratory findings to clinical applications, potentially leading to significant improvements in patient care by identifying optimal drug therapies.
Our company prides itself on its expertise in cellular biology and gene editing technologies, providing high-quality biological products that empower researchers to push the boundaries of current scientific knowledge. With our SLCO2B1 Gene Knockout Cell Lines, we contribute to the advancement of personalized medicine and pharmacogenomics, making a tangible impact on the future of health care.
Please note that all services are for research use only. Not intended for any clinical use.
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