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SLC7A1 Knockout Cell Lines

Gene: SLC7A1

Official Full Name: solute carrier family 7 member 1provided by HGNC

Gene Summary: Enables L-arginine transmembrane transporter activity; L-histidine transmembrane transporter activity; and L-lysine transmembrane transporter activity. Involved in carboxylic acid transport. Located in apical plasma membrane and basolateral plasma membrane. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO35390 SLC7A1 Knockout cell line (HeLa) Human SLC7A1 1:3~1:6 Negative Online Inquiry
KO35391 SLC7A1 Knockout cell line (HCT 116) Human SLC7A1 1:2~1:4 Negative Online Inquiry
KO35392 SLC7A1 Knockout cell line (HEK293) Human SLC7A1 1:3~1:6 Negative Online Inquiry
KO35393 SLC7A1 Knockout cell line (A549) Human SLC7A1 1:3~1:4 Negative Online Inquiry

Background

SLC7A1 Gene Knockout Cell Lines are genetically engineered cellular models that have had the SLC7A1 gene, which encodes for a cationic amino acid transporter, inactivated or deleted. This process typically involves the use of CRISPR/Cas9 technology, enabling precise alterations at the genomic level. The primary function of SLC7A1 is to facilitate the transport of amino acids across the cell membrane, playing a critical role in cellular metabolism, protein synthesis, and overall cellular homeostasis. By creating knockout cell lines, researchers can investigate the downstream effects of SLC7A1 deficiency on cellular functions and metabolic pathways, providing insights into the physiological roles of this transporter.

The scientific importance of SLC7A1 gene knockout cell lines extends to various research fields, including developmental biology, pharmacology, and toxicology. They serve as invaluable tools in studying conditions linked to amino acid transport dysregulation, such as certain metabolic disorders and cancers. In clinical settings, these cell lines can be employed to assess drug efficacy, toxicity, and the biological processes underlying disease mechanisms, thereby informing therapeutic strategies.

One of the unique selling points of our SLC7A1 Gene Knockout Cell Lines is their high specificity and reproducibility, ensuring consistent experimental results. Compared to alternative models, which may involve transient expressions or overexpression, these knockout cell lines provide a steady platform for long-term studies, leading to more robust and interpretable data. Additionally, our cell lines are thoroughly characterized, enabling researchers to swiftly integrate them into their work without the need for extensive validation.

For researchers and clinicians aiming to elucidate the role of amino acid transport in health and disease, our SLC7A1 Gene Knockout Cell Lines represent a valuable resource. They not only streamline the investigation process but also enhance the potential for significant discoveries that can lead to innovative treatments.

Our company prides itself on delivering high-quality, genetically modified cell lines tailored to meet the demands of cutting-edge research, backed by a commitment to scientific excellence and ongoing customer support to elevate your research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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