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SLC6A16 Knockout Cell Lines

Gene: SLC6A16

Official Full Name: solute carrier family 6 member 16provided by HGNC

Gene Summary: SLC6A16 shows structural characteristics of an Na(+)- and Cl(-)-dependent neurotransmitter transporter, including 12 transmembrane (TM) domains, intracellular N and C termini, and large extracellular loops containing multiple N-glycosylation sites.[supplied by OMIM, Mar 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27287 SLC6A16 Knockout cell line (HCT 116) Human SLC6A16 1:2~1:4 Negative Online Inquiry
KO27288 SLC6A16 Knockout cell line (HEK293) Human SLC6A16 1:3~1:6 Negative Online Inquiry
KO27289 SLC6A16 Knockout cell line (A549) Human SLC6A16 1:3~1:4 Negative Online Inquiry

Background

SLC6A16 Gene Knockout Cell Lines are genetically engineered cellular models designed to facilitate the study of the SLC6A16 gene, which encodes a member of the solute carrier family responsible for transporting essential nutrients such as amino acids across cellular membranes. These knockout cell lines have been meticulously created using CRISPR-Cas9 technology to introduce targeted mutations that disrupt SLC6A16 gene expression, providing researchers with a powerful tool to investigate the physiological and pathological roles of this transporter in various biological contexts.

The key function of the SLC6A16 gene knockout cell lines lies in their ability to elucidate the impact of SLC6A16 deficiency on cellular transport mechanisms and metabolic pathways. By analyzing these cell lines, researchers can observe changes in nutrient uptake, cellular proliferation, and signaling pathways that are often altered in diseases such as cancer, metabolic syndrome, and neurodegenerative disorders. The knockout model allows for precise assessments of the gene's role, enabling scientists to connect genetic loss to specific cellular phenotypes.

From a scientific perspective, the SLC6A16 knockout cell lines serve as crucial platforms for understanding the gene's involvement in transport-related disorders and their therapeutic implications. In clinical research settings, they can be utilized to screen for potential drug candidates or to investigate the efficacy of therapeutic interventions aimed at reversing the effects of SLC6A16 loss. This makes them invaluable for both academic research and pharmaceutical development endeavors.

What sets our SLC6A16 Gene Knockout Cell Lines apart from alternative models is their high specificity and reproducibility, ensuring that results are both reliable and applicable across various experimental conditions. Additionally, our cell lines are designed for ease of use, featuring robust growth characteristics and compatibility with standard cell culture practices, making them accessible to laboratories of all sizes.

Ultimately, adopting our SLC6A16 Gene Knockout Cell Lines will elevate your research by providing deep insights into nutrient transport and its cellular complications. With our extensive expertise in genetic engineering and cell line development, we are committed to delivering high-quality biological products that empower researchers and clinicians to achieve robust, meaningful results in their work.

Please note that all services are for research use only. Not intended for any clinical use.

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